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Amniotic fluid C-reactive protein as a predictor of infection in caesarean section: a feasibility study

Overview of attention for article published in Scientific Reports, April 2018
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Title
Amniotic fluid C-reactive protein as a predictor of infection in caesarean section: a feasibility study
Published in
Scientific Reports, April 2018
DOI 10.1038/s41598-018-24569-8
Pubmed ID
Authors

Zbigniew Marchocki, Angela Vinturache, Kevin Collins, Paddy O’ Reilly, Keelin O’Donoghue

Abstract

This study evaluated the feasibility of maternal C-reactive protein (CRP) in amniotic fluid (AF) as a predictor of post-partum infection in women who undergo emergency or elective caesarean section (CS). AF bacterial culture and levels of hs-CRP in maternal serum and AF were evaluated in Day 0 and three days thereafter (Day 3) in 79 women undergoing CS. Univariate analyses assessed the clinical and demographic characteristics, whereas the ROC curves assessed the feasibility of hs-CRP as marker of inflammation in women who undergo CS. There was no difference in AF, Day 0, and Day 3 serum hs-CRP levels between women with sterile compared to those with bacterial growth in AF. Among women with positive AF cultures, AF and Day 0 serum hs-CRP levels were higher in women who underwent emergency compared to those who had elective CS (p = 0.04, and p = 0.02 respectively). hs-CRP in Day 0 and Day 3 serum but not in AF has a fair predictor value of infection in emergency CS only (AUC 0.767; 95% CI 0.606-0.928, and AUC 0.791; 95% CI 0.645-0.036, respectively). We conclude that AF hs-CRP is not feasible in assessing the risk of post-cesarean inflammation or infection.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 20%
Lecturer > Senior Lecturer 2 13%
Other 2 13%
Student > Bachelor 2 13%
Student > Ph. D. Student 2 13%
Other 1 7%
Unknown 3 20%
Readers by discipline Count As %
Medicine and Dentistry 6 40%
Nursing and Health Professions 2 13%
Agricultural and Biological Sciences 2 13%
Sports and Recreations 1 7%
Biochemistry, Genetics and Molecular Biology 1 7%
Other 0 0%
Unknown 3 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 April 2018.
All research outputs
#20,483,282
of 23,045,021 outputs
Outputs from Scientific Reports
#106,461
of 124,488 outputs
Outputs of similar age
#287,605
of 326,557 outputs
Outputs of similar age from Scientific Reports
#2,916
of 3,376 outputs
Altmetric has tracked 23,045,021 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 124,488 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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