| Title |
Portal Vein Embolization Utilizing N-Butyl Cyanoacrylate for Contralateral Lobe Hypertrophy Prior to Liver Resection: A Systematic Review and Meta-Analysis
|
|---|---|
| Published in |
CardioVascular and Interventional Radiology, April 2018
|
| DOI | 10.1007/s00270-018-1964-6 |
| Pubmed ID | |
| Authors |
Ethan Wajswol, Tarek Jazmati, Sohail Contractor, Abhishek Kumar |
| Abstract |
To evaluate the safety and effectiveness of n-butyl cyanoacrylate (NBCA) for portal vein embolization (PVE) when used to induce contralateral future liver remnant (FLR) hypertrophy in patients undergoing planned hepatic resection for hepatic malignancy. The PubMed database (including articles indexed by MEDLINE) was searched for articles published from 1970 to 2018 describing patients treated with PVE utilizing NBCA to induce hypertrophy of the FLR prior to contralateral hepatic lobe resection. Demographic data, embolization technique, complications of embolization, resultant FLR hypertrophy, and surgical outcomes were obtained when available. A meta-analysis was performed to determine the cumulative relative hypertrophy rate of the FLR following PVE with NBCA. The literature search yielded 18 relevant articles. Six hundred and seven patients (383 men, 220 women; mean age 60.7 years) with procedures describing PVE utilizing NBCA were reviewed. The most common underlying hepatic malignancies were colorectal metastases (n = 348), followed by cholangiocarcinomas (n = 92), and hepatocellular carcinomas (n = 89). Technical success was reportedly achieved in 603/607 patients, for a success rate of 99.3%. Fixed effects meta-analysis of the relative hypertrophy rate of the FLR among studies resulted in an aggregate rate of 49.4 ± 1.3%. Of the patients who underwent attempted PVE, 461/607 (75.9%) eventually underwent surgical resection. Major complications following PVE occurred in 19 patients (3.13%), while minor complications following PVE occurred in 38 patients (6.26%). PVE utilizing NBCA to induce hypertrophy of the FLR prior to contralateral lobe resection in the setting of hepatic malignancy is safe and effective. Level IIa-Systematic review of cohort studies. |
X Demographics
The data shown below were collected from the profiles of 24 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 15 | 63% |
| Brazil | 1 | 4% |
| Peru | 1 | 4% |
| Greece | 1 | 4% |
| Argentina | 1 | 4% |
| Unknown | 5 | 21% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 10 | 42% |
| Practitioners (doctors, other healthcare professionals) | 8 | 33% |
| Scientists | 4 | 17% |
| Science communicators (journalists, bloggers, editors) | 2 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 35 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 6 | 17% |
| Student > Postgraduate | 5 | 14% |
| Student > Doctoral Student | 3 | 9% |
| Other | 3 | 9% |
| Student > Ph. D. Student | 3 | 9% |
| Other | 7 | 20% |
| Unknown | 8 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 21 | 60% |
| Biochemistry, Genetics and Molecular Biology | 2 | 6% |
| Energy | 1 | 3% |
| Nursing and Health Professions | 1 | 3% |
| Unknown | 10 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 November 2019.
All research outputs
#2,101,396
of 23,940,484 outputs
Outputs from CardioVascular and Interventional Radiology
#63
of 2,510 outputs
Outputs of similar age
#45,268
of 330,012 outputs
Outputs of similar age from CardioVascular and Interventional Radiology
#5
of 57 outputs
Altmetric has tracked 23,940,484 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,510 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,012 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.