Title |
IDENTIFICATION OF A NOVEL CELL TYPE IN PERIPHERAL LYMPHOID ORGANS OF MICE
|
---|---|
Published in |
The Journal of Experimental Medicine, May 1973
|
DOI | 10.1084/jem.137.5.1142 |
Pubmed ID | |
Authors |
Ralph M. Steinman, Zanvil A. Cohn |
Abstract |
A novel cell type has been identified in adherent cell populations prepared from mouse peripheral lymphoid organs (spleen, lymph node, Peyer's patch). Though present in small numbers (0.1-1.6% of the total nucleated cells) the cells have distinct morphological features. The nucleus is large, retractile, contorted in shape, and contains small nucleoli (usually two). The abundant cytoplasm is arranged in processes of varying length and width and contains many large spherical mitochondria. In the living state, the cells undergo characteristic movements, and unlike macrophages, do not appear to engage in active endocytosis. The term, dendritic cell, is proposed for this novel cell type. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 22 | 28% |
Korea, Republic of | 11 | 14% |
United Kingdom | 5 | 6% |
France | 3 | 4% |
Spain | 2 | 3% |
Canada | 2 | 3% |
Sweden | 1 | 1% |
Netherlands | 1 | 1% |
Italy | 1 | 1% |
Other | 6 | 8% |
Unknown | 25 | 32% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 47 | 59% |
Scientists | 24 | 30% |
Science communicators (journalists, bloggers, editors) | 6 | 8% |
Practitioners (doctors, other healthcare professionals) | 2 | 3% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | <1% |
United States | 3 | <1% |
Germany | 2 | <1% |
France | 2 | <1% |
Brazil | 2 | <1% |
Ireland | 1 | <1% |
Portugal | 1 | <1% |
Denmark | 1 | <1% |
Chile | 1 | <1% |
Other | 2 | <1% |
Unknown | 848 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 211 | 24% |
Student > Master | 136 | 16% |
Student > Bachelor | 113 | 13% |
Researcher | 93 | 11% |
Student > Doctoral Student | 66 | 8% |
Other | 88 | 10% |
Unknown | 159 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 195 | 23% |
Immunology and Microbiology | 173 | 20% |
Biochemistry, Genetics and Molecular Biology | 127 | 15% |
Medicine and Dentistry | 119 | 14% |
Chemistry | 19 | 2% |
Other | 59 | 7% |
Unknown | 174 | 20% |