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Redox theory of aging

Overview of attention for article published in Redox Biology, April 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Citations

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158 Dimensions

Readers on

mendeley
212 Mendeley
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1 CiteULike
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Title
Redox theory of aging
Published in
Redox Biology, April 2015
DOI 10.1016/j.redox.2015.03.004
Pubmed ID
Authors

Dean P. Jones

Abstract

Metazoan genomes encode exposure memory systems to enhance survival and reproductive potential by providing mechanisms for an individual to adjust during lifespan to environmental resources and challenges. These systems are inherently redox networks, arising during evolution of complex systems with O2 as a major determinant of bioenergetics, metabolic and structural organization, defense, and reproduction. The network structure decreases flexibility from conception onward due to differentiation and cumulative responses to environment (exposome). The redox theory of aging is that aging is a decline in plasticity of genome-exposome interaction that occurs as a consequence of execution of differentiation and exposure memory systems. This includes compromised mitochondrial and bioenergetic flexibility, impaired food utilization and metabolic homeostasis, decreased barrier and defense capabilities and loss of reproductive fidelity and fecundity. This theory accounts for hallmarks of aging, including failure to maintain oxidative or xenobiotic defenses, mitochondrial integrity, proteostasis, barrier structures, DNA repair, telomeres, immune function, metabolic regulation and regenerative capacity.

X Demographics

X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 212 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 1%
Spain 2 <1%
Brazil 1 <1%
Denmark 1 <1%
South Africa 1 <1%
Greece 1 <1%
United Kingdom 1 <1%
Unknown 202 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 39 18%
Student > Ph. D. Student 26 12%
Student > Bachelor 25 12%
Student > Master 24 11%
Student > Postgraduate 10 5%
Other 41 19%
Unknown 47 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 48 23%
Biochemistry, Genetics and Molecular Biology 47 22%
Medicine and Dentistry 21 10%
Chemistry 10 5%
Nursing and Health Professions 6 3%
Other 24 11%
Unknown 56 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 28. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 November 2023.
All research outputs
#1,371,989
of 25,371,288 outputs
Outputs from Redox Biology
#118
of 2,039 outputs
Outputs of similar age
#17,319
of 278,624 outputs
Outputs of similar age from Redox Biology
#2
of 14 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,039 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.4. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,624 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.