| Title |
Obesity and bone metabolism
|
|---|---|
| Published in |
Hormones international journal of endocrinology and metabolism, April 2018
|
| DOI | 10.1007/s42000-018-0018-4 |
| Pubmed ID | |
| Authors |
Christos Savvidis, Symeon Tournis, Anastasia D. Dede |
| Abstract |
The interaction between obesity and bone metabolism is complex. The effects of fat on the skeleton are mediated by both mechanical and biochemical factors. Though obesity is characterized by higher bone mineral density, studies conducted on bone microarchitecture have produced conflicting results. The majority of studies indicate that obesity has a positive effect on skeletal strength, even though most likely the effects are site-dependent and, in fact, obese individuals might be at risk of certain types of fractures. Mechanical loading and higher lean mass are associated with improved outcomes, whereas systemic inflammation, observed especially with abdominal obesity, may exert negative effects. Weight loss interventions likely lead to bone loss over time. Pharmacological treatment options seem to be safe in terms of skeletal health; however, the skeletal effects of bariatric surgery are dependent on the type of surgical procedure. Malabsorptive procedures are associated with higher short-term adverse effects on bone health. In this narrative review, we discuss the effects of obesity and weight loss interventions on skeletal health. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 117 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 117 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 18 | 15% |
| Student > Ph. D. Student | 11 | 9% |
| Student > Master | 10 | 9% |
| Researcher | 8 | 7% |
| Professor > Associate Professor | 7 | 6% |
| Other | 21 | 18% |
| Unknown | 42 | 36% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 23 | 20% |
| Biochemistry, Genetics and Molecular Biology | 9 | 8% |
| Nursing and Health Professions | 7 | 6% |
| Sports and Recreations | 7 | 6% |
| Agricultural and Biological Sciences | 4 | 3% |
| Other | 15 | 13% |
| Unknown | 52 | 44% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 October 2018.
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#20,663,600
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Outputs from Hormones international journal of endocrinology and metabolism
#334
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Outputs of similar age from Hormones international journal of endocrinology and metabolism
#19
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