| Title |
Disease burden of stroke in rural South Africa: an estimate of incidence, mortality and disability adjusted life years
|
|---|---|
| Published in |
BMC Neurology, April 2015
|
| DOI | 10.1186/s12883-015-0311-7 |
| Pubmed ID | |
| Authors |
Mandy Maredza, Melanie Y Bertram, Stephen M Tollman |
| Abstract |
In the context of an epidemiologic transition in South Africa, in which cardiovascular disease is increasing, little is known about the stroke burden, particularly morbidity in rural populations. Risk factors for stroke are high, with hypertension prevalence of more than 50%. Accurate, up-to-date information on disease burden is essential in planning health services for stroke management. This study estimates the burden of stroke in rural South Africa using the epidemiological parameters of incidence, mortality and disability adjusted life year (DALY) metric, a time-based measure that incorporates both mortality and morbidity. Data from the Agincourt health and socio-demographic surveillance system was utilised to calculate stroke mortality for the period 2007-2011. Dismod, an incidence-prevalence-mortality model, was used to estimate incidence and duration of disability in Agincourt sub-district and 'mostly rural' municipalities of South Africa. Using these values, burden of disease in years of life lost (YLL), years lived with disability (YLD) and DALYs was calculated for Agincourt sub-district. Over 5 years, there were an estimated 842 incident cases of stroke in Agincourt sub-district, a crude stroke incidence rate of 244 per 100,000 person years. We estimate that 1,070 DALYs are lost due to stroke yearly. Of this, YLDs contributed 8.7% (3.5 - 10.5%) in sensitivity analysis). Crude stroke mortality was 114 per 100,000 person-years in 2007-11 in Agincourt sub-district. Burden of stroke in entire rural South Africa, a population of some 13,000,000 people, was high, with an estimated 33, 500 strokes occurring in 2011. This study provides the first estimates of stroke burden in terms of incidence, and disability in rural South Africa. High YLL and DALYs lost amongst the rural populations demand urgent measures for preventing and mitigating impacts of stroke. Longitudinal surveillance sites provide a platform through which a changing stroke burden can be monitored in rural South Africa. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 335 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Bangladesh | 1 | <1% |
| South Africa | 1 | <1% |
| Unknown | 332 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 62 | 19% |
| Student > Bachelor | 39 | 12% |
| Researcher | 35 | 10% |
| Student > Postgraduate | 35 | 10% |
| Student > Ph. D. Student | 19 | 6% |
| Other | 65 | 19% |
| Unknown | 80 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 95 | 28% |
| Nursing and Health Professions | 69 | 21% |
| Social Sciences | 14 | 4% |
| Agricultural and Biological Sciences | 13 | 4% |
| Neuroscience | 9 | 3% |
| Other | 47 | 14% |
| Unknown | 88 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2015.
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#14,807,732
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Outputs from BMC Neurology
#1,354
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#148,663
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Outputs of similar age from BMC Neurology
#31
of 47 outputs
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