| Title |
Association of gender to outcome after out-of-hospital cardiac arrest – a report from the International Cardiac Arrest Registry
|
|---|---|
| Published in |
Critical Care, December 2015
|
| DOI | 10.1186/s13054-015-0904-y |
| Pubmed ID | |
| Authors |
Viktor Karlsson, Josef Dankiewicz, Niklas Nielsen, Karl B Kern, Michael R Mooney, Richard R Riker, Sten Rubertsson, David B Seder, Pascal Stammet, Kjetil Sunde, Eldar Søreide, Barbara T Unger, Hans Friberg |
| Abstract |
Previous studies have suggested an effect of gender on outcome after out-of-hospital cardiac arrest (OHCA), but the results are conflicting. We aimed to investigate the association of gender to outcome, coronary angiography (CAG) and adverse events in OHCA survivors treated with mild induced hypothermia (MIH). We performed a retrospective analysis of prospectively collected data from the International Cardiac Arrest Registry. Adult patients with a non-traumatic OHCA and treated with MIH were included. Good neurological outcome was defined as a cerebral performance category (CPC) of 1 or 2. A total of 1667 patients, 472 women (28%) and 1195 men (72%), met the inclusion criteria. Men were more likely to receive bystander cardiopulmonary resuscitation, have an initial shockable rhythm and to have a presumed cardiac cause of arrest. At hospital discharge, men had a higher survival rate (52% vs. 38%, p < 0.001) and more often a good neurological outcome (43% vs. 32%, p < 0.001) in the univariate analysis. When adjusting for baseline characteristics, male gender was associated with improved survival (OR 1.34, 95% CI: 1.01-1.78) but no longer with neurological outcome (OR 1.24, 95% CI: 0.92-1.67). Adverse events were common; women more often had hypokalemia, hypomagnesemia and bleeding requiring transfusion, while men had more pneumonia. In a subgroup analysis of patients with a presumed cardiac cause of arrest (n = 1361), men more often had CAG performed on admission (58% vs. 50%, p = 0.02) but this discrepancy disappeared in an adjusted analysis. Gender differences exist regarding cause of arrest, adverse events and outcome. Male gender was independently associated with survival but not with neurological outcome. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 25% |
| United Kingdom | 1 | 25% |
| Puerto Rico | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 50% |
| Practitioners (doctors, other healthcare professionals) | 2 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 1% |
| United States | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 96 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 10% |
| Student > Bachelor | 10 | 10% |
| Student > Master | 9 | 9% |
| Student > Ph. D. Student | 8 | 8% |
| Professor > Associate Professor | 8 | 8% |
| Other | 25 | 25% |
| Unknown | 29 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 48 | 48% |
| Nursing and Health Professions | 9 | 9% |
| Psychology | 4 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 1% |
| Biochemistry, Genetics and Molecular Biology | 1 | 1% |
| Other | 5 | 5% |
| Unknown | 31 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 May 2022.
All research outputs
#14,387,928
of 25,374,647 outputs
Outputs from Critical Care
#4,749
of 6,554 outputs
Outputs of similar age
#186,880
of 395,408 outputs
Outputs of similar age from Critical Care
#394
of 466 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
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