Title |
The potential usefulness of taurine on diabetes mellitus and its complications
|
---|---|
Published in |
Amino Acids, March 2011
|
DOI | 10.1007/s00726-011-0883-5 |
Pubmed ID | |
Authors |
Takashi Ito, Stephen W. Schaffer, Junichi Azuma |
Abstract |
Taurine (2-aminoethanesulfonic acid) is a free amino acid found ubiquitously in millimolar concentrations in all mammalian tissues. Taurine exerts a variety of biological actions, including antioxidation, modulation of ion movement, osmoregulation, modulation of neurotransmitters, and conjugation of bile acids, which may maintain physiological homeostasis. Recently, data is accumulating that show the effectiveness of taurine against diabetes mellitus, insulin resistance and its complications, including retinopathy, nephropathy, neuropathy, atherosclerosis and cardiomyopathy, independent of hypoglycemic effect in several animal models. The useful effects appear due to the multiple actions of taurine on cellular functions. This review summarizes the beneficial effects of taurine supplementation on diabetes mellitus and the molecular mechanisms underlying its effectiveness. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Spain | 2 | 17% |
Unknown | 10 | 83% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 11 | 92% |
Practitioners (doctors, other healthcare professionals) | 1 | 8% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Portugal | 1 | <1% |
Brazil | 1 | <1% |
Spain | 1 | <1% |
Japan | 1 | <1% |
United States | 1 | <1% |
Unknown | 155 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 28 | 18% |
Student > Bachelor | 28 | 18% |
Student > Master | 22 | 14% |
Student > Ph. D. Student | 19 | 12% |
Student > Doctoral Student | 14 | 9% |
Other | 27 | 17% |
Unknown | 22 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 40 | 25% |
Agricultural and Biological Sciences | 38 | 24% |
Biochemistry, Genetics and Molecular Biology | 16 | 10% |
Nursing and Health Professions | 9 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 9 | 6% |
Other | 28 | 18% |
Unknown | 20 | 13% |