| Title |
Identification and analytical characteristics of synthetic cannabinoids with an indazole-3-carboxamide structure bearing a N-1-methoxycarbonylalkyl group
|
|---|---|
| Published in |
Analytical & Bioanalytical Chemistry, April 2015
|
| DOI | 10.1007/s00216-015-8612-7 |
| Pubmed ID | |
| Authors |
Vadim Shevyrin, Vladimir Melkozerov, Alexander Nevero, Oleg Eltsov, Yuri Shafran, Yuri Morzherin, Albert T. Lebedev |
| Abstract |
Illicit new psychoactive substances (NPS) are a serious threat to health throughout the world. Such NPS do not usually pass preliminary pharmacological trials. In 2014, we identified a series of five new synthetic cannabinoids with an indazole-3-carboxamide structure bearing an N-1-methoxycarbonylalkyl group. The compounds have very high cannabimimetic activity which has caused mass severe intoxication and deaths. The compounds were identified by means of gas chromatography-mass spectrometry (GC-MS), including high-resolution mass spectrometry (GC-HRMS), ultra-high-performance liquid chromatography-high-resolution tandem mass spectrometry (UHPLC-HRMS(2)), and (1)H and (13)C nuclear magnetic resonance spectroscopy (NMR). The peculiarities of mass-spectral fragmentation of the compounds after electron ionization (EI) ionization and collision-induced dissociation (CID) were studied. The analytical characteristics reported for the compounds will enable their identification in a variety of materials seized from criminals. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 2 | 67% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Unknown | 54 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 10 | 18% |
| Researcher | 10 | 18% |
| Student > Ph. D. Student | 7 | 13% |
| Student > Master | 6 | 11% |
| Student > Postgraduate | 4 | 7% |
| Other | 4 | 7% |
| Unknown | 14 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 20 | 36% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 9% |
| Medicine and Dentistry | 4 | 7% |
| Agricultural and Biological Sciences | 3 | 5% |
| Neuroscience | 3 | 5% |
| Other | 4 | 7% |
| Unknown | 16 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 March 2020.
All research outputs
#2,471,554
of 26,017,215 outputs
Outputs from Analytical & Bioanalytical Chemistry
#174
of 9,818 outputs
Outputs of similar age
#30,632
of 283,743 outputs
Outputs of similar age from Analytical & Bioanalytical Chemistry
#2
of 180 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,818 research outputs from this source. They receive a mean Attention Score of 3.2. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 283,743 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 180 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.