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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Sleep Restores Behavioral Plasticity to Drosophila Mutants
|
|---|---|
| Published in |
Current Biology, April 2015
|
| DOI | 10.1016/j.cub.2015.03.027 |
| Pubmed ID | |
| Authors |
Stephane Dissel, Veena Angadi, Leonie Kirszenblat, Yasuko Suzuki, Jeff Donlea, Markus Klose, Zachary Koch, Denis English, Raphaelle Winsky-Sommerer, Bruno van Swinderen, Paul J. Shaw |
| Abstract |
Given the role that sleep plays in modulating plasticity, we hypothesized that increasing sleep would restore memory to canonical memory mutants without specifically rescuing the causal molecular lesion. Sleep was increased using three independent strategies: activating the dorsal fan-shaped body, increasing the expression of Fatty acid binding protein (dFabp), or by administering the GABA-A agonist 4,5,6,7-tetrahydroisoxazolo-[5,4-c]pyridine-3-ol (THIP). Short-term memory (STM) or long-term memory (LTM) was evaluated in rutabaga (rut) and dunce (dnc) mutants using aversive phototaxic suppression and courtship conditioning. Each of the three independent strategies increased sleep and restored memory to rut and dnc mutants. Importantly, inducing sleep also reverses memory defects in a Drosophila model of Alzheimer's disease. Together, these data demonstrate that sleep plays a more fundamental role in modulating behavioral plasticity than previously appreciated and suggest that increasing sleep may benefit patients with certain neurological disorders. |
X Demographics
The data shown below were collected from the profiles of 16 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 31% |
| United Kingdom | 3 | 19% |
| Australia | 1 | 6% |
| Canada | 1 | 6% |
| Israel | 1 | 6% |
| Hungary | 1 | 6% |
| Netherlands | 1 | 6% |
| Unknown | 3 | 19% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 8 | 50% |
| Members of the public | 7 | 44% |
| Science communicators (journalists, bloggers, editors) | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 236 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 1% |
| United States | 3 | 1% |
| Japan | 2 | <1% |
| Australia | 1 | <1% |
| Belgium | 1 | <1% |
| Netherlands | 1 | <1% |
| Mexico | 1 | <1% |
| China | 1 | <1% |
| Unknown | 223 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 55 | 23% |
| Student > Bachelor | 40 | 17% |
| Researcher | 39 | 17% |
| Student > Master | 23 | 10% |
| Professor > Associate Professor | 10 | 4% |
| Other | 31 | 13% |
| Unknown | 38 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 69 | 29% |
| Neuroscience | 60 | 25% |
| Biochemistry, Genetics and Molecular Biology | 43 | 18% |
| Medicine and Dentistry | 6 | 3% |
| Psychology | 4 | 2% |
| Other | 11 | 5% |
| Unknown | 43 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 121. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 April 2016.
All research outputs
#353,453
of 25,759,158 outputs
Outputs from Current Biology
#1,467
of 14,809 outputs
Outputs of similar age
#3,816
of 280,748 outputs
Outputs of similar age from Current Biology
#30
of 187 outputs
Altmetric has tracked 25,759,158 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 14,809 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 62.5. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,748 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 187 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.