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The effect of body–mind relaxation meditation induction on major depressive disorder: A resting-state fMRI study

Overview of attention for article published in Journal of Affective Disorders, April 2015
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

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1 news outlet
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4 X users
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4 Facebook pages

Citations

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27 Dimensions

Readers on

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194 Mendeley
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1 CiteULike
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Title
The effect of body–mind relaxation meditation induction on major depressive disorder: A resting-state fMRI study
Published in
Journal of Affective Disorders, April 2015
DOI 10.1016/j.jad.2015.04.030
Pubmed ID
Authors

Fangfang Chen, Xueyu Lv, Jiliang Fang, Shan Yu, Jing Sui, Lingzhong Fan, Tao Li, Yang Hong, XiaoLing Wang, Weidong Wang, Tianzi Jiang

Abstract

Meditation has been increasingly evaluated as an important complementary therapeutic tool for the treatment of depression. The present study employed resting-state functional magnetic resonance imaging (rs-fMRI) to examine the effect of body-mind relaxation meditation induction (BMRMI) on the brain activity of depressed patients and to investigate possible mechanisms of action for this complex intervention. 21 major depressive disorder patients (MDDs) and 24 age and gender-matched healthy controls (HCs) received rs-fMRI scans at baseline and after listening to a selection of audio designed to induce body-mind relaxation meditation. The rs-fMRI data were analyzed using Matlab toolbox to obtain the amplitude of low-frequency fluctuations (ALFF) of the BOLD signal for the whole brain. A mixed-design repeated measures analysis of variance (ANOVA) was performed on the whole brain to find which brain regions were affected by the BMRMI. An additional functional connectivity analysis was used to identify any atypical connection patterns after the BMRMI. After the BMRMI experience, both the MDDs and HCs showed decreased ALFF values in the bilateral frontal pole (BA10). Additionally, increased functional connectivity from the right dorsal medial prefrontal cortex (dmPFC) to the left dorsal lateral prefrontal cortex (dlPFC) and the left lateral orbitofrontal cortex (OFC) was identified only in the MDDs after the BMRMI. In order to exclude the impact of other events on the participants׳ brain activity, the Hamilton Rating Scales for Depression (HDRS) was not measured after the body-mind relaxation induction. Our findings support the hypothesis that body-mind relaxation meditation induction may regulate the activities of the prefrontal cortex and thus may have the potential to help patients construct reappraisal strategies that can modulate the brain activity in multiple emotion-processing systems.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 194 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 2 1%
United Kingdom 2 1%
Netherlands 1 <1%
Italy 1 <1%
Unknown 188 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 33 17%
Student > Bachelor 31 16%
Student > Ph. D. Student 30 15%
Researcher 21 11%
Student > Doctoral Student 11 6%
Other 33 17%
Unknown 35 18%
Readers by discipline Count As %
Psychology 59 30%
Neuroscience 24 12%
Medicine and Dentistry 22 11%
Agricultural and Biological Sciences 11 6%
Nursing and Health Professions 9 5%
Other 25 13%
Unknown 44 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 April 2023.
All research outputs
#2,721,544
of 25,374,647 outputs
Outputs from Journal of Affective Disorders
#1,756
of 10,146 outputs
Outputs of similar age
#33,925
of 279,305 outputs
Outputs of similar age from Journal of Affective Disorders
#26
of 181 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,146 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.4. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,305 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 181 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.