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[Spectrum-effect relationship of Moutan cortex against lipopolysaccharide-induced acute lung injury].

Overview of attention for article published in Zhongguo Zhong yao za zhi Zhongguo zhongyao zazhi China journal of Chinese materia medica, November 2014
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Title
[Spectrum-effect relationship of Moutan cortex against lipopolysaccharide-induced acute lung injury].
Published in
Zhongguo Zhong yao za zhi Zhongguo zhongyao zazhi China journal of Chinese materia medica, November 2014
DOI 10.4268/cjcmm20142222
Pubmed ID
Authors

Ming-jie Tang, Yong-shan Ye, Qi Zhang, Jian Li, Hai-min Lei, Cheng-ke Cai, Qiang Li

Abstract

This research is to study the relationship between HPLC fingerprints of Moutan Cortex, Paeoniae Radix Rubra and Paeoniae Radix Alba and their activity on lipopolysaccharide-induced acute lung injury. HPLC fingerprints of each extract of Moutan Cortex,Paeoniae Radix Rubra and Paeoniae Radix Alba were established by an optimized HPLC-MS method. The activities of all samples against protein and tumor necrosis a factor were tested by the model of lipopolysaccharide-induced acute lung injury. The possible relationship between HPLC-MS fingerprints and the activitieswere deduced by the Partial least squares regression analysis method. Samples were analyzed by HPLC-MS/MS to identify the major peaks. The results showed that each sample had some effect on acute lung injury. Four components with a lager contribution rate of efficacy were calculated by the research of spectrum-effect relationship. Moutan Cortex exhibited good activity on acute lung injury, and gallic acid, paeoniflorin, galloylpaeoniflorin and paeonol were the main effective components.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 2 40%
Researcher 2 40%
Student > Ph. D. Student 1 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 2 40%
Chemistry 2 40%
Medicine and Dentistry 1 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 April 2015.
All research outputs
#22,760,732
of 25,377,790 outputs
Outputs from Zhongguo Zhong yao za zhi Zhongguo zhongyao zazhi China journal of Chinese materia medica
#738
of 1,528 outputs
Outputs of similar age
#228,863
of 268,536 outputs
Outputs of similar age from Zhongguo Zhong yao za zhi Zhongguo zhongyao zazhi China journal of Chinese materia medica
#17
of 45 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,528 research outputs from this source. They receive a mean Attention Score of 1.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,536 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.