Title |
In vitro antimicrobial studies of silver carbene complexes: activity of free and nanoparticle carbene formulations against clinical isolates of pathogenic bacteria
|
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Published in |
Journal of Antimicrobial Chemotherapy (JAC), October 2011
|
DOI | 10.1093/jac/dkr408 |
Pubmed ID | |
Authors |
Jeff G. Leid, Andrew J. Ditto, Amanda Knapp, Parth N. Shah, Brian D. Wright, Robyn Blust, Lanette Christensen, C. B. Clemons, J. P. Wilber, Gerald W. Young, Ae Gyeong Kang, Matthew J. Panzner, Carolyn L. Cannon, Yang H. Yun, Wiley J. Youngs, Nicole M. Seckinger, Emily K. Cope |
Abstract |
Silver carbenes may represent novel, broad-spectrum antimicrobial agents that have low toxicity while providing varying chemistry for targeted applications. Here, the bactericidal activity of four silver carbene complexes (SCCs) with different formulations, including nanoparticles (NPs) and micelles, was tested against a panel of clinical strains of bacteria and fungi that are the causative agents of many skin and soft tissue, respiratory, wound, blood, and nosocomial infections. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 50% |
Japan | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Germany | 1 | <1% |
Unknown | 145 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 28 | 19% |
Researcher | 24 | 16% |
Student > Master | 21 | 14% |
Student > Bachelor | 18 | 12% |
Student > Doctoral Student | 8 | 5% |
Other | 24 | 16% |
Unknown | 24 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 23 | 16% |
Chemistry | 21 | 14% |
Agricultural and Biological Sciences | 19 | 13% |
Medicine and Dentistry | 14 | 10% |
Immunology and Microbiology | 11 | 7% |
Other | 33 | 22% |
Unknown | 26 | 18% |