| Title |
Distinct Functional States of Astrocytes During Sleep and Wakefulness: Is Norepinephrine the Master Regulator?
|
|---|---|
| Published in |
Current Sleep Medicine Reports, January 2015
|
| DOI | 10.1007/s40675-014-0004-6 |
| Pubmed ID | |
| Authors |
John O’Donnell, Fengfei Ding, Maiken Nedergaard |
| Abstract |
Astrocytes are the chief supportive cells in the central nervous system, but work over the past 20 years have documented that astrocytes also contribute to complex neural processes, such as working memory. Recent discoveries of norepinephrine-mediated astrocytic Ca(2+) responses have raised the possibility that astrocytic activity in the adult brain is driven by global responses to changes in behavioral state. Moreover, analysis of the interstitial space volume suggests that astrocytes may undergo changes in cell volume in response to activation of norepinephrine receptors. This review will focus on what is known about astrocytic functions within the nervous system, and how these functions interrelate with rapid changes in behavioral state mediated by norepinephrine signaling. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Canada | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 138 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 2 | 1% |
| United States | 2 | 1% |
| France | 1 | <1% |
| Unknown | 133 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 26 | 19% |
| Student > Master | 23 | 17% |
| Student > Ph. D. Student | 22 | 16% |
| Student > Bachelor | 17 | 12% |
| Professor > Associate Professor | 8 | 6% |
| Other | 21 | 15% |
| Unknown | 21 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 43 | 31% |
| Agricultural and Biological Sciences | 28 | 20% |
| Medicine and Dentistry | 13 | 9% |
| Biochemistry, Genetics and Molecular Biology | 10 | 7% |
| Immunology and Microbiology | 3 | 2% |
| Other | 12 | 9% |
| Unknown | 29 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2023.
All research outputs
#14,415,395
of 24,795,084 outputs
Outputs from Current Sleep Medicine Reports
#74
of 131 outputs
Outputs of similar age
#180,215
of 364,365 outputs
Outputs of similar age from Current Sleep Medicine Reports
#2
of 6 outputs
Altmetric has tracked 24,795,084 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 131 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 19.3. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 364,365 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.