| Title |
The involvement of purinergic signalling in obesity
|
|---|---|
| Published in |
Purinergic Signalling, April 2018
|
| DOI | 10.1007/s11302-018-9605-8 |
| Pubmed ID | |
| Authors |
Geoffrey Burnstock, Daniela Gentile |
| Abstract |
Obesity is a growing worldwide health problem, with an alarming increasing prevalence in developed countries, caused by a dysregulation of energy balance. Currently, no wholly successful pharmacological treatments are available for obesity and related adverse consequences. In recent years, hints obtained from several experimental animal models support the notion that purinergic signalling, acting through ATP-gated ion channels (P2X), G protein-coupled receptors (P2Y) and adenosine receptors (P1), is involved in obesity, both at peripheral and central levels. This review has drawn together, for the first time, the evidence for a promising, much needed novel therapeutic purinergic signalling approach for the treatment of obesity with a 'proof of concept' that hopefully could lead to further investigations and clinical trials for the management of obesity. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 54 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 8 | 15% |
| Student > Ph. D. Student | 7 | 13% |
| Researcher | 7 | 13% |
| Student > Master | 6 | 11% |
| Student > Doctoral Student | 4 | 7% |
| Other | 8 | 15% |
| Unknown | 14 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 17 | 31% |
| Agricultural and Biological Sciences | 5 | 9% |
| Medicine and Dentistry | 4 | 7% |
| Neuroscience | 3 | 6% |
| Nursing and Health Professions | 2 | 4% |
| Other | 5 | 9% |
| Unknown | 18 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 July 2018.
All research outputs
#20,483,282
of 23,045,021 outputs
Outputs from Purinergic Signalling
#294
of 380 outputs
Outputs of similar age
#290,554
of 329,136 outputs
Outputs of similar age from Purinergic Signalling
#3
of 4 outputs
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