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Cross-talk between Epstein-Barr virus and microenvironment in the pathogenesis of lymphomas

Overview of attention for article published in Seminars in Cancer Biology, May 2015
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Title
Cross-talk between Epstein-Barr virus and microenvironment in the pathogenesis of lymphomas
Published in
Seminars in Cancer Biology, May 2015
DOI 10.1016/j.semcancer.2015.04.006
Pubmed ID
Authors

Riccardo Dolcetti

Abstract

Epstein-Bar virus (EBV) is known to directly drive the neoplastic transformation of lymphoid cells resulting in the development of a variety of lymphoproliferative disorders. Emerging evidence however indicates that this final outcome is also related to the ability of EBV to shape microenvironment making it more conducive to cell transformation. Indeed, EBV up-regulates the production of several soluble factors promoting the growth and/or the survival of lymphoid cells and orchestrates a variety of complex mechanisms favoring their escape from anti-tumor immune responses. Furthermore, EBV-infected B lymphocytes actively secrete exosomes and recent investigation is now shedding light on the content and functional impact that these bioactive vesicles may have in bystander recipient cells. The complex interplay existing between EBV-carrying lymphoid cells and tumor microenvironment is now offering attractive targets of therapy that can be exploited to improve current therapeutic strategies for EBV-driven lymphoid malignancies.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Italy 1 1%
Unknown 71 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 21%
Researcher 11 15%
Student > Bachelor 9 12%
Student > Master 8 11%
Other 5 7%
Other 16 22%
Unknown 9 12%
Readers by discipline Count As %
Medicine and Dentistry 31 42%
Agricultural and Biological Sciences 13 18%
Biochemistry, Genetics and Molecular Biology 10 14%
Immunology and Microbiology 3 4%
Nursing and Health Professions 1 1%
Other 3 4%
Unknown 12 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 October 2020.
All research outputs
#20,031,563
of 25,483,400 outputs
Outputs from Seminars in Cancer Biology
#1,109
of 1,451 outputs
Outputs of similar age
#193,213
of 279,222 outputs
Outputs of similar age from Seminars in Cancer Biology
#14
of 16 outputs
Altmetric has tracked 25,483,400 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,451 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,222 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.