| Title |
ACTN3 R577X polymorphism is not associated with team sport athletic status in Italians
|
|---|---|
| Published in |
Sports Medicine - Open, March 2015
|
| DOI | 10.1186/s40798-015-0008-x |
| Pubmed ID | |
| Authors |
Myosotis Massidda, Valeria Bachis, Laura Corrias, Francesco Piras, Marco Scorcu, Claudia Culigioni, Daniele Masala, Carla M Calò |
| Abstract |
The ACTN3 gene may influence performance in team sports, in which sprint action and high-speed movements, regulated by the anaerobic energy system, are crucial to the ultimate success of a match. The aim of this study was to determine the association between the ACTN3 R577X (rs1815739) polymorphism and elite team sport athletic status in Italian male athletes. We compared the genotype and allele frequency of the ACTN3 R577X polymorphism between team sport athletes (n = 75), endurance athletes (n = 40), sprint/power athletes (n = 64), and non-athletic healthy controls (n = 192) from Italy. Genomic DNA was collected using a buccal swab. Extraction was performed according to the manufacturer's directions provided with a commercially available kit (Qiagen S.r.l., Milan, Italy). Team sport athletes showed a lower frequency of the 577RR genotype compared to the 577XX genotype than sprint/power athletes (p = 0.044). However, the ACTN3 R577X polymorphism was not associated with team sport athletic status compared to endurance athletes and non-athletic controls. Our results agree with a recent large-scale study involving athletes from Spain, Poland, and Russia. The ACTN3 R577X polymorphism was not associated with team sport athletic status compared to endurance athletes and non-athletic controls. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 72 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 11 | 15% |
| Student > Bachelor | 11 | 15% |
| Student > Ph. D. Student | 10 | 14% |
| Student > Doctoral Student | 7 | 10% |
| Researcher | 5 | 7% |
| Other | 8 | 11% |
| Unknown | 20 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Sports and Recreations | 21 | 29% |
| Biochemistry, Genetics and Molecular Biology | 10 | 14% |
| Agricultural and Biological Sciences | 5 | 7% |
| Nursing and Health Professions | 3 | 4% |
| Arts and Humanities | 2 | 3% |
| Other | 6 | 8% |
| Unknown | 25 | 35% |
Attention Score in Context
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All research outputs
#18,471,305
of 22,888,307 outputs
Outputs from Sports Medicine - Open
#444
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#192,859
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Outputs of similar age from Sports Medicine - Open
#11
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