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Hepcidin: regulation of the master iron regulator

Overview of attention for article published in Bioscience Reports, May 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

twitter
8 X users
facebook
1 Facebook page
wikipedia
1 Wikipedia page
googleplus
2 Google+ users

Citations

dimensions_citation
169 Dimensions

Readers on

mendeley
246 Mendeley
citeulike
1 CiteULike
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Title
Hepcidin: regulation of the master iron regulator
Published in
Bioscience Reports, May 2015
DOI 10.1042/bsr20150014
Pubmed ID
Authors

Gautam Rishi, Daniel F. Wallace, V. Nathan Subramaniam

Abstract

Iron, an essential nutrient, is required for many diverse biological processes. The absence of a defined pathway to excrete excess iron makes it essential for the body to regulate the amount of iron absorbed; a deficiency could lead to iron deficiency and an excess to iron overload, and associated disorders such as anemia and hemochromatosis, respectively. This regulation is mediated by the iron-regulatory hormone hepcidin. Hepcidin binds to the only known iron export protein, ferroportin, inducing its internalization and degradation, thus limiting the amount of iron released into the blood. The major factors that are implicated in hepcidin regulation include iron stores, hypoxia, inflammation and erythropoiesis. This review summarizes our present knowledge about the molecular mechanisms and signaling pathways contributing to hepcidin regulation by these factors.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 246 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Poland 1 <1%
Germany 1 <1%
France 1 <1%
Unknown 242 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 36 15%
Student > Bachelor 36 15%
Student > Master 28 11%
Researcher 25 10%
Student > Doctoral Student 17 7%
Other 42 17%
Unknown 62 25%
Readers by discipline Count As %
Medicine and Dentistry 59 24%
Biochemistry, Genetics and Molecular Biology 41 17%
Agricultural and Biological Sciences 26 11%
Immunology and Microbiology 9 4%
Nursing and Health Professions 8 3%
Other 28 11%
Unknown 75 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 February 2024.
All research outputs
#3,633,818
of 25,547,904 outputs
Outputs from Bioscience Reports
#113
of 2,046 outputs
Outputs of similar age
#44,975
of 280,423 outputs
Outputs of similar age from Bioscience Reports
#4
of 31 outputs
Altmetric has tracked 25,547,904 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,046 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,423 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.