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Pain Control

Overview of attention for book
Cover of 'Pain Control'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Emerging Concepts of Pain Therapy Based on Neuronal Mechanisms
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    Chapter 2 The pharmacology of nociceptor priming.
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    Chapter 3 Sodium channels and pain.
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    Chapter 4 Role of Nerve Growth Factor in Pain
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    Chapter 5 Central Sensitization in Humans: Assessment and Pharmacology
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    Chapter 6 Nitric Oxide-Mediated Pain Processing in the Spinal Cord
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    Chapter 7 The role of the endocannabinoid system in pain.
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    Chapter 8 The role of glia in the spinal cord in neuropathic and inflammatory pain.
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    Chapter 9 Plasticity of inhibition in the spinal cord.
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    Chapter 10 Modulation of peripheral inflammation by the spinal cord.
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    Chapter 11 The Relationship Between Opioids and Immune Signalling in the Spinal Cord
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    Chapter 12 The Role of Proteases in Pain
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    Chapter 13 Amygdala Pain Mechanisms
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    Chapter 14 Itch and Pain Differences and Commonalities
Attention for Chapter 11: The Relationship Between Opioids and Immune Signalling in the Spinal Cord
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Chapter title
The Relationship Between Opioids and Immune Signalling in the Spinal Cord
Chapter number 11
Book title
Pain Control
Published in
Handbook of experimental pharmacology, January 2015
DOI 10.1007/978-3-662-46450-2_11
Pubmed ID
25846621
Book ISBNs
978-3-66-246449-6, 978-3-66-246450-2
Authors

Thomas, Jacob, Mustafa, Sanam, Johnson, Jacinta, Nicotra, Lauren, Hutchinson, Mark, Jacob Thomas, Sanam Mustafa, Jacinta Johnson, Lauren Nicotra, Mark Hutchinson

Editors

Schaible, Hans-Georg

Abstract

Opioids are considered the gold standard for the treatment of moderate to severe pain. However, heterogeneity in analgesic efficacy, poor potency and side effects are associated with opioid use, resulting in dose limitations and suboptimal pain management. Traditionally thought to exhibit their analgesic actions via the activation of the neuronal G-protein-coupled opioid receptors, it is now widely accepted that neuronal activity of opioids cannot fully explain the initiation and maintenance of opioid tolerance, hyperalgesia and allodynia. In this review we will highlight the evidence supporting the role of non-neuronal mechanisms in opioid signalling, paying particular attention to the relationship of opioids and immune signalling.

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X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 4%
Unknown 23 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 25%
Student > Ph. D. Student 3 13%
Student > Bachelor 2 8%
Unspecified 2 8%
Student > Doctoral Student 1 4%
Other 5 21%
Unknown 5 21%
Readers by discipline Count As %
Medicine and Dentistry 5 21%
Neuroscience 5 21%
Biochemistry, Genetics and Molecular Biology 2 8%
Unspecified 2 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Other 5 21%
Unknown 4 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 July 2015.
All research outputs
#20,941,392
of 23,577,654 outputs
Outputs from Handbook of experimental pharmacology
#577
of 654 outputs
Outputs of similar age
#299,666
of 356,631 outputs
Outputs of similar age from Handbook of experimental pharmacology
#58
of 66 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 654 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 356,631 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 66 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.

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