Title |
Design of the RINSE Trial: The Rapid Infusion of cold Normal Saline by paramedics during CPR
|
---|---|
Published in |
BMC Emergency Medicine, October 2011
|
DOI | 10.1186/1471-227x-11-17 |
Pubmed ID | |
Authors |
Conor Deasy, Stephen Bernard, Peter Cameron, Ian Jacobs, Karen Smith, Cindy Hein, Hugh Grantham, Judith Finn, the RINSE investigators |
Abstract |
The International Liaison Committee on Resuscitation (ILCOR) now recommends therapeutic hypothermia (TH) (33 °C for 12-24 hours) as soon as possible for patients who remain comatose after resuscitation from shockable rhythm in out-of-hospital cardiac arrest and that it be considered for non shockable rhythms. The optimal timing of TH is still uncertain. Laboratory data have suggested that there is significantly decreased neurological injury if cooling is initiated during CPR. In addition, peri-arrest cooling may increase the rate of successful defibrillation. This study aims to determine whether paramedic cooling during CPR improves outcome compared standard treatment in patients who are being resuscitated from out-of-hospital cardiac arrest. |
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