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Convective transport of highly plasma protein bound drugs facilitates direct penetration into deep tissues after topical application

Overview of attention for article published in British Journal of Clinical Pharmacology, March 2012
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Title
Convective transport of highly plasma protein bound drugs facilitates direct penetration into deep tissues after topical application
Published in
British Journal of Clinical Pharmacology, March 2012
DOI 10.1111/j.1365-2125.2011.04128.x
Pubmed ID
Authors

Yuri Dancik, Yuri G. Anissimov, Owen G. Jepps, Michael S. Roberts

Abstract

Many products are applied to human skin for local effects in deeper tissues. Animal studies suggest that deep dermal and/or subcutaneous delivery may be facilitated by both dermal diffusion and transport via the cutaneous vasculature. However, the relationship between the extent and pathways of penetration, drug physicochemical properties and deeper tissue physiology is not well understood.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Australia 1 1%
Unknown 75 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 22%
Student > Ph. D. Student 13 17%
Student > Master 7 9%
Student > Bachelor 6 8%
Student > Doctoral Student 4 5%
Other 10 13%
Unknown 19 25%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 14 18%
Medicine and Dentistry 14 18%
Agricultural and Biological Sciences 10 13%
Chemistry 3 4%
Engineering 3 4%
Other 10 13%
Unknown 22 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 October 2011.
All research outputs
#19,944,994
of 25,374,647 outputs
Outputs from British Journal of Clinical Pharmacology
#4,502
of 5,465 outputs
Outputs of similar age
#128,305
of 168,814 outputs
Outputs of similar age from British Journal of Clinical Pharmacology
#29
of 37 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,465 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 168,814 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.