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Feasibility and acceptability of a remotely administered computerized intervention to address cognitive late effects among childhood cancer survivors

Overview of attention for article published in Neuro-Oncology Practice, March 2015
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Title
Feasibility and acceptability of a remotely administered computerized intervention to address cognitive late effects among childhood cancer survivors
Published in
Neuro-Oncology Practice, March 2015
DOI 10.1093/nop/npu036
Pubmed ID
Authors

Lauren E. Cox, Jason M. Ashford, Kellie N. Clark, Karen Martin-Elbahesh, Kristina K. Hardy, Thomas E. Merchant, Robert J. Ogg, Sima Jeha, Victoria W. Willard, Lu Huang, Hui Zhang, Heather M. Conklin

Abstract

Childhood cancer survivors frequently develop working memory (WM) deficits as a result of disease and treatment. Medication-based and therapist-delivered interventions are promising but have limitations. Computerized interventions completed at home may be more appealing for survivors. We evaluated the feasibility and acceptability of a remotely administered, computerized WM intervention (Cogmed) for pediatric cancer survivors using a single-blind, randomized, wait-list control design. Of 80 qualifying patients, 12 were excluded or declined to participate. Participants randomized to intervention (n = 34/68) included survivors of childhood brain tumors (32%) or acute lymphoblastic leukemia (ALL; 68%) between the ages of 8 and 16 years ([Formula: see text] = 12.2) who were at least 1 year post therapy ([Formula: see text] = 5.0). The majority of brain tumor participants were treated with cranial radiation therapy (72.7%), whereas most of the ALL participants were treated with chemotherapy only (87%). Participants completed 25 WM training sessions over 5-9 weeks at home with weekly phone-based coaching. Participants lived in 16 states. Compliance was strong, with 30 of the 34 participants (88%) completing intervention. Almost all participants completed pre- and postintervention neuroimaging exams (91% and 93%, respectively). Families had the necessary skills to utilize the computer program successfully. Caregivers reported they were generally able to find time to complete training (63%), viewed training as beneficial (70%), and would recommend this intervention to others (93%). Cogmed is a feasible and acceptable intervention for childhood cancer survivors. It is a viable option for survivors who do not live in close proximity to cancer care centers. Efficacy and neural correlates of change are currently being evaluated.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 <1%
Unknown 118 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 18%
Student > Master 20 17%
Researcher 10 8%
Student > Bachelor 10 8%
Student > Doctoral Student 7 6%
Other 14 12%
Unknown 36 30%
Readers by discipline Count As %
Psychology 30 25%
Medicine and Dentistry 16 13%
Neuroscience 13 11%
Nursing and Health Professions 12 10%
Social Sciences 3 3%
Other 8 7%
Unknown 37 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 April 2016.
All research outputs
#16,722,190
of 25,374,917 outputs
Outputs from Neuro-Oncology Practice
#248
of 386 outputs
Outputs of similar age
#158,943
of 276,645 outputs
Outputs of similar age from Neuro-Oncology Practice
#4
of 8 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 386 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,645 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.