Title |
The effects of simvastatin on angiogenesis: studied by an original model of atherosclerosis and acute myocardial infarction in rabbit
|
---|---|
Published in |
Molecular Biology Reports, November 2010
|
DOI | 10.1007/s11033-010-0497-0 |
Pubmed ID | |
Authors |
Wei Shen, Hai-Ming Shi, Wei-Hu Fan, Xin-Ping Luo, Bo Jin, Yong Li |
Abstract |
Statins have shown pleiotropic effects, many of them independent of their impact on lipids. Angiogenesis can be beneficial in the acute myocardial infarction to improve circulation. However, it also can be harmful due to worsening of atherosclerosis. Here, we established a new minimal invasive rabbit model to study ischemic myocardium and atherosclerosis together to mimic clinical scenario. We demonstrated that simvastatin has the effect of pro-angiogenesis and further improve cardiac function in ischemic myocardium, as well as the effect of anti-angiogenesis to improve atherosclerosis in aorta vessels. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Indonesia | 1 | 5% |
United States | 1 | 5% |
Unknown | 17 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Professor > Associate Professor | 3 | 16% |
Researcher | 3 | 16% |
Student > Bachelor | 2 | 11% |
Student > Master | 2 | 11% |
Student > Ph. D. Student | 2 | 11% |
Other | 4 | 21% |
Unknown | 3 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 6 | 32% |
Agricultural and Biological Sciences | 4 | 21% |
Biochemistry, Genetics and Molecular Biology | 2 | 11% |
Engineering | 2 | 11% |
Energy | 1 | 5% |
Other | 2 | 11% |
Unknown | 2 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 October 2011.
All research outputs
#20,147,309
of 22,653,392 outputs
Outputs from Molecular Biology Reports
#2,016
of 2,872 outputs
Outputs of similar age
#169,612
of 179,835 outputs
Outputs of similar age from Molecular Biology Reports
#31
of 32 outputs
Altmetric has tracked 22,653,392 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,872 research outputs from this source. They receive a mean Attention Score of 2.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 179,835 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.