| Title |
Postoperative recovery after anesthesia in morbidly obese patients: a systematic review and meta-analysis of randomized controlled trials
|
|---|---|
| Published in |
Canadian Journal of Anesthesia/Journal canadien d'anesthésie, May 2015
|
| DOI | 10.1007/s12630-015-0405-0 |
| Pubmed ID | |
| Authors |
Feng-Lin Liu, Yih-Giun Cherng, Shin-Yan Chen, Yen-Hao Su, Shih-Yu Huang, Po-Han Lo, Yen-Ying Lee, Ka-Wai Tam |
| Abstract |
Obese patients present a challenge to safe general anesthesia because of impaired cardiopulmonary physiology and increased risks of aspiration and acute upper airway obstruction. Since studies are lacking regarding the postoperative effects on recovery from general anesthesia in morbidly obese patients, we conducted a systematic review and meta-analysis of recovery outcomes in morbidly obese patients who had undergone general anesthesia. We systematically searched the PubMed, EMBASE™, Cochrane, and Scopus™ databases for randomized controlled trials that evaluated the outcome of anesthesia with desflurane, sevoflurane, isoflurane, or propofol in morbidly obese patients. Using a random effects model, we conducted meta-analyses to assess recovery times (eye opening, hand squeezing, tracheal extubation, and stating name or birth date), time to discharge from the postanesthesia care unit (PACU), and the incidence and severity of postoperative nausea and vomiting (PONV). We reviewed results for 11 trials and found that patients given desflurane took less time: to respond to commands to open their eyes (weighted mean difference [WMD] -3.10 min; 95% confidence interval (CI): -5.13 to -1.08), to squeeze the investigator's hand (WMD -7.83 min; 95% CI: -8.81 to -6.84), to be prepared for tracheal extubation (WMD -3.88 min; 95% CI: -7.42 to -0.34), and to state their name (WMD -7.15 min; 95% CI: -11.00 to -3.30). We did not find significant differences in PACU discharge times, PONV, or the PACU analgesic requirement. Postoperative recovery was significantly faster after desflurane than after sevoflurane, isoflurane, or propofol anesthesia in obese patients. No clinically relevant differences were observed regarding PACU discharge time, incidence of PONV, or postoperative pain scores. The systematic review was registered with PROSPERO (CRD42014009480). |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 26 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Doctoral Student | 3 | 12% |
| Student > Master | 3 | 12% |
| Other | 2 | 8% |
| Student > Postgraduate | 2 | 8% |
| Student > Bachelor | 1 | 4% |
| Other | 3 | 12% |
| Unknown | 12 | 46% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 9 | 35% |
| Nursing and Health Professions | 3 | 12% |
| Immunology and Microbiology | 1 | 4% |
| Engineering | 1 | 4% |
| Unknown | 12 | 46% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 August 2015.
All research outputs
#17,302,400
of 25,394,764 outputs
Outputs from Canadian Journal of Anesthesia/Journal canadien d'anesthésie
#2,321
of 2,881 outputs
Outputs of similar age
#168,955
of 281,706 outputs
Outputs of similar age from Canadian Journal of Anesthesia/Journal canadien d'anesthésie
#20
of 33 outputs
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