You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Podoplanin: An emerging cancer biomarker and therapeutic target
|
|---|---|
| Published in |
Cancer Science, May 2018
|
| DOI | 10.1111/cas.13580 |
| Pubmed ID | |
| Authors |
Harini Krishnan, Julie Rayes, Tomoyuki Miyashita, Genichiro Ishii, Edward P. Retzbach, Stephanie A. Sheehan, Ai Takemoto, Yao‐Wen Chang, Kazue Yoneda, Jun Asai, Lasse Jensen, Lushun Chalise, Atsushi Natsume, Gary S. Goldberg |
| Abstract |
Podoplanin (PDPN) is a transmembrane receptor glycoprotein that is upregulated on transformed cells, cancer associated fibroblasts (CAFs), and inflammatory macrophages that contribute to cancer progression. In particular, PDPN increases tumor cell clonal capacity, epithelial mesenchymal transition (EMT), migration, invasion, metastasis, and inflammation. Antibodies, CAR-T cells, biologics, and synthetic compounds that target PDPN can inhibit cancer progression and septic inflammation in preclinical models. This review describes recent advances in how PDPN may be used as a biomarker and therapeutic target for many types of cancer including glioma, squamous cell carcinoma, mesothelioma, and melanoma. This article is protected by copyright. All rights reserved. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 137 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 137 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 26 | 19% |
| Researcher | 18 | 13% |
| Student > Bachelor | 14 | 10% |
| Student > Master | 12 | 9% |
| Student > Doctoral Student | 6 | 4% |
| Other | 19 | 14% |
| Unknown | 42 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 30 | 22% |
| Biochemistry, Genetics and Molecular Biology | 30 | 22% |
| Agricultural and Biological Sciences | 11 | 8% |
| Immunology and Microbiology | 6 | 4% |
| Veterinary Science and Veterinary Medicine | 4 | 3% |
| Other | 8 | 6% |
| Unknown | 48 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 January 2023.
All research outputs
#3,703,710
of 23,565,002 outputs
Outputs from Cancer Science
#289
of 2,761 outputs
Outputs of similar age
#71,222
of 329,541 outputs
Outputs of similar age from Cancer Science
#4
of 44 outputs
Altmetric has tracked 23,565,002 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,761 research outputs from this source. They receive a mean Attention Score of 4.2. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,541 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.