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Bariatric surgery increases risk of bone fracture

Overview of attention for article published in Surgical Endoscopy, April 2018
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Title
Bariatric surgery increases risk of bone fracture
Published in
Surgical Endoscopy, April 2018
DOI 10.1007/s00464-017-5628-4
Pubmed ID
Authors

Anna Z. Fashandi, J. Hunter Mehaffey, Robert B. Hawkins, Bruce Schirmer, Peter T. Hallowell

Abstract

The purpose of this study was to determine the long-term incidence of bone fracture after bariatric surgery, identify specific risk factors for fracture, and compare these data to baseline risk in a comorbidity-matched morbidly obese population. We hypothesize that, despite prior studies with conflicting results, bariatric surgery increases a patient's long-term risk of fracture. All patients who underwent bariatric surgery at a single institution 1985-2015 were reviewed. Univariate analysis of patient demographic data including comorbidities, insurance payer status, procedure type, and BMI was performed. Multivariate logistic regression was used to identify independent predictors of fracture in this population. Finally, we identified a propensity-matched control group of morbidly obese patients from our institutional Clinical Data Repository in the same timeframe who did not undergo bariatric surgery to determine expected rate of fracture without bariatric surgery. A total of 3439 patients underwent bariatric surgery, with 220 (6.4%) patients experiencing a bone fracture at mean follow-up of 7.6 years. On multivariate logistic regression, independent predictors of increased fracture included tobacco use and Roux-en-Y gastric bypass while private insurance and race were protective (table). Additionally, 1:1 matching on all comorbidity and demographic factors identified 3880 patients (1940 surgical patients) with equal propensity to undergo bariatric surgery. Between the propensity-matched cohorts, patients who had a history of bariatric surgery were more than twice as likely to experience a fracture as those who did not (6.4 vs. 2.7%, p < 0.0001). This study of bariatric surgery patients at our institution identified several independent predictors of postoperative fracture. Additionally, these long-term data demonstrate patients who had bariatric surgery are at a significantly increased risk of bone fracture compared to a propensity-matched control group. Future efforts need to focus on nutrient screening and risk modification to reduce the impact of this long-term complication.

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Geographical breakdown

Country Count As %
Unknown 42 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 12%
Librarian 4 10%
Student > Bachelor 4 10%
Student > Doctoral Student 3 7%
Student > Master 3 7%
Other 7 17%
Unknown 16 38%
Readers by discipline Count As %
Medicine and Dentistry 13 31%
Biochemistry, Genetics and Molecular Biology 3 7%
Sports and Recreations 2 5%
Agricultural and Biological Sciences 1 2%
Computer Science 1 2%
Other 5 12%
Unknown 17 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 May 2018.
All research outputs
#20,485,225
of 23,047,237 outputs
Outputs from Surgical Endoscopy
#5,722
of 6,111 outputs
Outputs of similar age
#286,474
of 325,398 outputs
Outputs of similar age from Surgical Endoscopy
#94
of 98 outputs
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