| Title |
Treatment of diabetes with encapsulated pig islets: an update on current developments
|
|---|---|
| Published in |
Journal of Zhejiang University - Science B, May 2015
|
| DOI | 10.1631/jzus.b1400310 |
| Pubmed ID | |
| Authors |
Hai-tao Zhu, Lu Lu, Xing-yu Liu, Liang Yu, Yi Lyu, Bo Wang |
| Abstract |
The potential use of allogeneic islet transplantation in curing type 1 diabetes mellitus has been adequately demonstrated, but its large-scale application is limited by the short supply of donor islets and the need for sustained and heavy immunosuppressive therapy. Encapsulation of pig islets was therefore suggested with a view to providing a possible alternative source of islet grafts and avoiding chronic immunosuppression and associated adverse or toxic effects. Nevertheless, several vital elements should be taken into account before this therapy becomes a clinical reality, including cell sources, encapsulation approaches, and implantation sites. This paper provides a comprehensive review of xenotransplantation of encapsulated pig islets for the treatment of type 1 diabetes mellitus, including current research findings and suggestions for future studies. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 81 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 21 | 26% |
| Student > Ph. D. Student | 14 | 17% |
| Student > Master | 13 | 16% |
| Researcher | 6 | 7% |
| Student > Doctoral Student | 4 | 5% |
| Other | 6 | 7% |
| Unknown | 17 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 17 | 21% |
| Agricultural and Biological Sciences | 13 | 16% |
| Engineering | 8 | 10% |
| Medicine and Dentistry | 8 | 10% |
| Chemistry | 5 | 6% |
| Other | 10 | 12% |
| Unknown | 20 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 78. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 May 2023.
All research outputs
#545,654
of 25,373,627 outputs
Outputs from Journal of Zhejiang University - Science B
#8
of 704 outputs
Outputs of similar age
#6,167
of 279,135 outputs
Outputs of similar age from Journal of Zhejiang University - Science B
#1
of 15 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 704 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,135 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.