Title |
Mortality Rate and Predictors in Children Under 15 Years Old Who Acquired HIV from Mother to Child Transmission in Paraguay
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Published in |
AIDS and Behavior, February 2018
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DOI | 10.1007/s10461-018-2053-1 |
Pubmed ID | |
Authors |
Gloria Aguilar, Angélica Espinosa Miranda, George W. Rutherford, Sergio Munoz, Nancy Hills, Tania Samudio, Fernando Galeano, Anibal Kawabata, Carlos Miguel Rios González |
Abstract |
We estimated mortality rate and predictors of death in children and adolescents who acquired HIV through mother-to-child transmission in Paraguay. In 2000-2014, we conducted a cohort study among children and adolescents aged < 15 years. We abstracted data from medical records and death certificates. We used the Cox proportional hazards model for the multivariable analysis of mortality predictors. A total of 302 subjects were included in the survey; 216 (71.5%) were younger than 5 years, 148 (51.0%) were male, and 214 (70.9%) resided in the Asunción metropolitan area. There were 52 (17.2%) deaths, resulting in an overall mortality rate of 2.06 deaths per 100 person-years. The children and adolescents with hemoglobin levels ≤ 9 g/dL at baseline had a 2-times higher hazard of death compared with those who had levels > 9 g/dL (HR 2.27, 95% CI 1.01-5.10). The mortality of HIV-infected children and adolescents in Paraguay is high, and anemia is associated with mortality. Improving prenatal screening to find cases earlier and improving pediatric follow-up are needed. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 33 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Doctoral Student | 5 | 15% |
Researcher | 5 | 15% |
Student > Master | 5 | 15% |
Student > Bachelor | 3 | 9% |
Other | 2 | 6% |
Other | 2 | 6% |
Unknown | 11 | 33% |
Readers by discipline | Count | As % |
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Nursing and Health Professions | 9 | 27% |
Medicine and Dentistry | 7 | 21% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 6% |
Social Sciences | 2 | 6% |
Psychology | 1 | 3% |
Other | 0 | 0% |
Unknown | 12 | 36% |