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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Dietary supplementation with Allium hirtifolium and/or Astragalus hamosus improved memory and reduced neuro-inflammation in the rat model of Alzheimer’s disease
|
|---|---|
| Published in |
Applied Physiology, Nutrition, and Metabolism, December 2017
|
| DOI | 10.1139/apnm-2017-0585 |
| Pubmed ID | |
| Authors |
Zahra Bahaeddin, Asal Yans, Fariba Khodagholi, Shamim Sahranavard |
| Abstract |
Allium hirtifolium Boiss and Astragalus hamosus L. are mentioned in Iranian traditional medicine documentation as therapy for a kind of dementia with the features and symptoms similar to those of Alzheimer's disease (AD). In the present study, the effects of these herbs on neuro-inflammation and memory have been evaluated as new therapies in amyloid beta (Aβ) induced memory impairment model. Separate groups of rats were fed with A. hirtifolium or A. hamosus extract (both 100 mg/kg/day) started one week before stereotaxic surgery to 24 hours before behavioral testing (totally, for 16 successive days). The effects of oral administration of mentioned extracts on the memory and neuro-inflammation were assessed in the Aβ-injected rats. The results of this study showed that oral administration of both A. hirtifolium and A. hamosus improved the memory, examined by using Y-maze test and shuttle box apparatus. Also, Western blotting analysis of cyclooxygenase-2, interleukin-1β and tumor necrosis factor-α showed that these herbs have ameliorating effects against the neuro-inflammation caused by Aβ. These findings suggest that the use of A. hirtifolium and A. hamosus as herbal therapy may be suitable for decreasing AD-related symptoms and treatment of other neurodegenerative disorders.. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 32 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 6 | 19% |
| Student > Doctoral Student | 3 | 9% |
| Researcher | 3 | 9% |
| Student > Master | 3 | 9% |
| Other | 2 | 6% |
| Other | 8 | 25% |
| Unknown | 7 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Nursing and Health Professions | 5 | 16% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 13% |
| Psychology | 4 | 13% |
| Chemistry | 2 | 6% |
| Biochemistry, Genetics and Molecular Biology | 2 | 6% |
| Other | 8 | 25% |
| Unknown | 7 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 May 2018.
All research outputs
#15,989,045
of 25,382,440 outputs
Outputs from Applied Physiology, Nutrition, and Metabolism
#1,501
of 2,327 outputs
Outputs of similar age
#251,893
of 447,701 outputs
Outputs of similar age from Applied Physiology, Nutrition, and Metabolism
#31
of 50 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 36th percentile – i.e., 36% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,327 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.9. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 447,701 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.