| Title |
Identification and developmental expression of new biomineralization proteins in the sea urchin Strongylocentrotus purpuratus
|
|---|---|
| Published in |
Development Genes and Evolution, September 2002
|
| DOI | 10.1007/s00427-002-0261-0 |
| Pubmed ID | |
| Authors |
Michele R. Illies, Margaret T. Peeler, Anna M. Dechtiaruk, Charles A. Ettensohn |
| Abstract |
The endoskeleton of the sea urchin larva is a network of calcareous rods secreted by primary mesenchyme cells (PMCs). In this study, we identified seven new biomineralization-related proteins through an analysis of a large database of gene products expressed by PMCs. The proteins include three new spicule matrix proteins (SpSM29, SpSM32, and SpC-lectin), two proteins related to the PMC-specific cell surface glycoprotein MSP130 (MSP130-related-1 and -2), and two novel proteins (SpP16 and SpP19). The genes encoding these proteins are expressed specifically by cells of the large micromere-PMC lineage and are activated zygotically beginning at the blastula stage, prior to PMC ingression. Several of the mRNAs show regulated patterns of expression within the PMC syncytium that correlate with the pattern of skeletal rod growth. This work identifies new proteins that may regulate the process of biomineralization in this tractable model system. |
Mendeley readers
The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Belgium | 3 | 6% |
| Japan | 1 | 2% |
| France | 1 | 2% |
| Mexico | 1 | 2% |
| Unknown | 48 | 89% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 30% |
| Researcher | 11 | 20% |
| Student > Master | 10 | 19% |
| Professor > Associate Professor | 5 | 9% |
| Student > Bachelor | 3 | 6% |
| Other | 3 | 6% |
| Unknown | 6 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 35 | 65% |
| Biochemistry, Genetics and Molecular Biology | 7 | 13% |
| Environmental Science | 2 | 4% |
| Physics and Astronomy | 1 | 2% |
| Earth and Planetary Sciences | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 6 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 June 2015.
All research outputs
#4,369,982
of 25,374,917 outputs
Outputs from Development Genes and Evolution
#53
of 509 outputs
Outputs of similar age
#7,258
of 49,017 outputs
Outputs of similar age from Development Genes and Evolution
#1
of 3 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 509 research outputs from this source. They receive a mean Attention Score of 4.5. This one has done well, scoring higher than 89% of its peers.
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We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them