Title |
Rapidly progressive fatal idiopathic hypertrophic pachymeningitis with brainstem involvement in a child
|
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Published in |
Child's Nervous System, May 2018
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DOI | 10.1007/s00381-018-3819-5 |
Pubmed ID | |
Authors |
Kosuke Tsuchida, Shinobu Fukumura, Akiyo Yamamoto, Yukinori Akiyama, Hiroshi Hirano, Hiroyuki Tsutsumi |
Abstract |
Hypertrophic pachymeningitis (HP) is a rare disorder characterized by diffuse thickening of the dura mater with resultant neurologic deficits. HP develops secondary to various conditions or idiopathically usually in adults but rarely in children. We describe a 3-year-old female child with idiopathic HP. Her HP involved the entire central nervous system with progression into the brainstem. The lesion responded poorly to pulsed steroids or any immunosuppressants. The brainstem lesion grew rapidly and formed various nodules that ultimately resulted in brain death. This is the first fatal case of HP in a child. |
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United States | 1 | 100% |
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Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
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Unknown | 8 | 100% |
Demographic breakdown
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Student > Doctoral Student | 2 | 25% |
Other | 2 | 25% |
Lecturer > Senior Lecturer | 1 | 13% |
Student > Bachelor | 1 | 13% |
Professor | 1 | 13% |
Other | 0 | 0% |
Unknown | 1 | 13% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 5 | 63% |
Biochemistry, Genetics and Molecular Biology | 1 | 13% |
Unknown | 2 | 25% |