| Title |
All-cause mortality in a nationwide cohort of childhood-onset diabetes in Norway 1973–2013
|
|---|---|
| Published in |
Diabetologia, May 2015
|
| DOI | 10.1007/s00125-015-3623-7 |
| Pubmed ID | |
| Authors |
Vibeke Gagnum, Lars C. Stene, Leiv Sandvik, Morten W. Fagerland, Pål R. Njølstad, Geir Joner, Torild Skrivarhaug |
| Abstract |
The aim of this study was to assess the association between all-cause mortality and sex, age at diagnosis and year of diagnosis in Norwegian patients with childhood-onset diabetes. The study was based on the nationwide, population-based Norwegian Childhood Diabetes Registry, which includes all newly diagnosed cases of childhood-onset diabetes at age 0-14 years in 1973-1982 and 1989-2012 (n = 7,884). Patients were followed until date of death, emigration or 30 September 2013. Among the 7,884 patients, representing 132,420 person-years, 249 (3.2%) died during a mean follow-up of 16.8 (range 0.0-40.7) years. The standardised mortality ratio (SMR) for the total cohort was 3.6 (95% CI 3.1, 4.0), increasing by attained age. Absolute mortality was significantly lower in females than in males (HR 0.50 [95% CI 0.38, 0.65]), although the SMRs were similar. Cox regression analysis showed a significant decrease in mortality of 49% (HR 0.51 [95% CI 0.28, 0.93]) for those diagnosed in 1999-2012 compared with those diagnosed in 1973-1982 (p = 0.03). In spite of improved diabetes care, mortality is still three to four times higher in those with childhood-onset diabetes compared with the general population in Norway. However, absolute mortality has declined among children diagnosed most recently (1999-2012) compared with those diagnosed in the earliest period (1973-1982). |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 4% |
| Unknown | 26 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 6 | 22% |
| Student > Ph. D. Student | 5 | 19% |
| Student > Postgraduate | 3 | 11% |
| Student > Doctoral Student | 2 | 7% |
| Researcher | 2 | 7% |
| Other | 6 | 22% |
| Unknown | 3 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 16 | 59% |
| Nursing and Health Professions | 2 | 7% |
| Mathematics | 1 | 4% |
| Arts and Humanities | 1 | 4% |
| Agricultural and Biological Sciences | 1 | 4% |
| Other | 1 | 4% |
| Unknown | 5 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 June 2015.
All research outputs
#17,760,015
of 22,808,725 outputs
Outputs from Diabetologia
#4,616
of 5,036 outputs
Outputs of similar age
#179,395
of 264,439 outputs
Outputs of similar age from Diabetologia
#63
of 73 outputs
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