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Mendeley readers
Attention Score in Context
| Title |
The interleukin-10 family of cytokines
|
|---|---|
| Published in |
Trends in Immunology, February 2002
|
| DOI | 10.1016/s1471-4906(01)02149-4 |
| Pubmed ID | |
| Authors |
Helmut Fickenscher, Simon Hör, Heide Küpers, Andrea Knappe, Sabine Wittmann, Heinrich Sticht |
| Abstract |
A family of interleukin-10 (IL-10)-related cytokines has emerged, comprising a series of herpesviral and poxviral members and several cellular sequence paralogs, including IL-19, IL-20, IL-22 [IL-10-related T-cell-derived inducible factor (IL-TIF)], IL-24 [melanoma differentiation-associated antigen 7 (MDA-7)] and IL-26 (AK155). Although the predicted helical structure of these homodimeric molecules is conserved, certain receptor-binding residues are variable and define the interaction with specific heterodimers of different type-2 cytokine receptors. This leads, through the activation of signal transducer and activator of transcription (STAT) factors, to diverse biological effects. For example, whereas IL-10 is a well-studied pleiotropic immunosuppressive and immunostimulatory cytokine, IL-22/IL-TIF mediates acute-phase response signals in hepatocytes and IL-20 induces the hyperproliferation of keratinocytes, which has been proposed as a pathogenic mechanism of psoriasis. |
Mendeley readers
The data shown below were compiled from readership statistics for 121 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 2% |
| Germany | 1 | <1% |
| India | 1 | <1% |
| France | 1 | <1% |
| Egypt | 1 | <1% |
| Costa Rica | 1 | <1% |
| Unknown | 113 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 27 | 22% |
| Student > Ph. D. Student | 20 | 17% |
| Student > Master | 15 | 12% |
| Student > Bachelor | 12 | 10% |
| Professor > Associate Professor | 8 | 7% |
| Other | 23 | 19% |
| Unknown | 16 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 40 | 33% |
| Medicine and Dentistry | 30 | 25% |
| Biochemistry, Genetics and Molecular Biology | 8 | 7% |
| Immunology and Microbiology | 8 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 4% |
| Other | 11 | 9% |
| Unknown | 19 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 December 2020.
All research outputs
#2,863,575
of 25,373,627 outputs
Outputs from Trends in Immunology
#500
of 2,635 outputs
Outputs of similar age
#5,864
of 132,983 outputs
Outputs of similar age from Trends in Immunology
#1
of 17 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,635 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.2. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 132,983 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.