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Blood Monocytes: Development, Heterogeneity, and Relationship with Dendritic Cells

Overview of attention for article published in Annual Review of Immunology, April 2009
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (58th percentile)

Mentioned by

blogs
1 blog
patent
41 patents

Citations

dimensions_citation
1290 Dimensions

Readers on

mendeley
1531 Mendeley
citeulike
3 CiteULike
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Title
Blood Monocytes: Development, Heterogeneity, and Relationship with Dendritic Cells
Published in
Annual Review of Immunology, April 2009
DOI 10.1146/annurev.immunol.021908.132557
Pubmed ID
Authors

Cedric Auffray, Michael H. Sieweke, Frederic Geissmann

Abstract

Monocytes are circulating blood leukocytes that play important roles in the inflammatory response, which is essential for the innate response to pathogens. But inflammation and monocytes are also involved in the pathogenesis of inflammatory diseases, including atherosclerosis. In adult mice, monocytes originate in the bone marrow in a Csf-1R (MCSF-R, CD115)-dependent manner from a hematopoietic precursor common for monocytes and several subsets of macrophages and dendritic cells (DCs). Monocyte heterogeneity has long been recognized, but in recent years investigators have identified three functional subsets of human monocytes and two subsets of mouse monocytes that exert specific roles in homeostasis and inflammation in vivo, reminiscent of those of the previously described classically and alternatively activated macrophages. Functional characterization of monocytes is in progress in humans and rodents and will provide a better understanding of the pathophysiology of inflammation.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 1,531 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 23 2%
Germany 13 <1%
United Kingdom 10 <1%
Netherlands 5 <1%
Brazil 4 <1%
Denmark 3 <1%
Canada 3 <1%
France 2 <1%
Ireland 2 <1%
Other 24 2%
Unknown 1442 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 404 26%
Researcher 302 20%
Student > Master 166 11%
Student > Bachelor 142 9%
Student > Doctoral Student 94 6%
Other 246 16%
Unknown 177 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 575 38%
Medicine and Dentistry 259 17%
Immunology and Microbiology 197 13%
Biochemistry, Genetics and Molecular Biology 142 9%
Pharmacology, Toxicology and Pharmaceutical Science 30 2%
Other 125 8%
Unknown 203 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 March 2024.
All research outputs
#2,815,346
of 23,524,722 outputs
Outputs from Annual Review of Immunology
#263
of 923 outputs
Outputs of similar age
#9,564
of 95,383 outputs
Outputs of similar age from Annual Review of Immunology
#10
of 24 outputs
Altmetric has tracked 23,524,722 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 923 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.7. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,383 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.