Title |
Synthesis and properties of hydroxyapatite/poly-L-lactide composite biomaterials
|
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Published in |
Clinical Materials, May 1999
|
DOI | 10.1016/s0142-9612(98)00234-8 |
Pubmed ID | |
Authors |
Nenad Ignjatović, Simonida Tomić, Momčilo Dakić, Miroslav Miljković, Milenko Plavšić, Dragan Uskoković |
Abstract |
Calcium hydroxyapatite (HAp) and poly-L-lactide (PLLA) were synthesized chemically. The obtained HAp was of high purity and, after special thermal treatment, of high crystallinity as well. Synthesis of PLLA was performed using L-lactide as a monomer and nontoxic initiator. In this way a polymer of large molar weight (about 400,000) was obtained. The HAp and PLLA obtained were used as constituents of the HAp/PLLA composite biomaterial, a potential material for implants. The composite was obtained by mixing completely dissolved PLLA with granules of HAp. The composite was compacted by cold and hot pressing at pressures of 49.0-490.5 MPa and temperatures of 20-184 degrees C. The material obtained at optimum process parameters had a density of 99.6% and compressive strength of 93.2 MPa. |
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Geographical breakdown
Country | Count | As % |
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Israel | 1 | <1% |
India | 1 | <1% |
Iran, Islamic Republic of | 1 | <1% |
Japan | 1 | <1% |
Poland | 1 | <1% |
Serbia | 1 | <1% |
Unknown | 100 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 28 | 26% |
Researcher | 18 | 17% |
Student > Doctoral Student | 9 | 8% |
Student > Master | 9 | 8% |
Student > Bachelor | 8 | 8% |
Other | 13 | 12% |
Unknown | 21 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Materials Science | 21 | 20% |
Engineering | 20 | 19% |
Chemistry | 15 | 14% |
Agricultural and Biological Sciences | 9 | 8% |
Chemical Engineering | 7 | 7% |
Other | 6 | 6% |
Unknown | 28 | 26% |