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Recruitment and Immobilization of a Fluorinated Biomarker Across an Interfacial Phospholipid Film using a Fluorocarbon Gas

Overview of attention for article published in Angewandte Chemie. International Edition, June 2015
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Title
Recruitment and Immobilization of a Fluorinated Biomarker Across an Interfacial Phospholipid Film using a Fluorocarbon Gas
Published in
Angewandte Chemie. International Edition, June 2015
DOI 10.1002/anie.201502677
Pubmed ID
Authors

Guang Yang, Miriam O'Duill, Véronique Gouverneur, Marie Pierre Krafft

Abstract

Perfluorohexane gas when introduced in the air atmosphere above a film of phospholipid self-supported on an aqueous solution of C2 F5 -labeled compounds causes the recruitment and immobilization of the latter in the interfacial film. When the phospholipid forms a liquid-condensed Gibbs monolayer, which is the case for dipalmitoylphosphatidylcholine (DPPC), the C2 F5 -labeled molecule remains trapped in the monolayer after removal of F-hexane. Investigations involve bubble profile analysis tensiometry (Gibbs films), Langmuir monolayers and microbubble experiments. The new phenomenon was utilized to incorporate a hypoxia biomarker, a C2 F5 -labeled nitrosoimidazole (EF5), in microbubble shells. This finding opens perspectives in the delivery of fluorinated therapeutic molecules and biomarkers.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 4%
Unknown 22 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 17%
Student > Ph. D. Student 4 17%
Student > Master 3 13%
Professor > Associate Professor 2 9%
Other 1 4%
Other 2 9%
Unknown 7 30%
Readers by discipline Count As %
Chemistry 7 30%
Pharmacology, Toxicology and Pharmaceutical Science 2 9%
Engineering 2 9%
Physics and Astronomy 1 4%
Environmental Science 1 4%
Other 2 9%
Unknown 8 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 June 2015.
All research outputs
#19,962,154
of 25,394,764 outputs
Outputs from Angewandte Chemie. International Edition
#40,906
of 50,044 outputs
Outputs of similar age
#191,985
of 280,152 outputs
Outputs of similar age from Angewandte Chemie. International Edition
#648
of 833 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 50,044 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,152 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 833 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.