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Survival outcomes in patients with multiple primary melanomas

Overview of attention for article published in Journal of the European Academy of Dermatology & Venereology, April 2015
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Title
Survival outcomes in patients with multiple primary melanomas
Published in
Journal of the European Academy of Dermatology & Venereology, April 2015
DOI 10.1111/jdv.13144
Pubmed ID
Authors

C.J. Rowe, M.H. Law, J.M. Palmer, S. MacGregor, N.K. Hayward, K. Khosrotehrani

Abstract

A substantial number of melanoma patients will develop multiple primary melanomas (MPM). Currently, little is known about the impact of MPM on survival. We aimed to determine whether melanoma survival is worse for patients with MPM compared to those with a single invasive primary melanoma (SPM). A cohort study was conducted. Patients were sourced from an Australian population, with follow-up information collected retrospectively from registry data. Melanoma-specific survival analysis was performed to find associated variables after adjustment for known prognostic factors, using four different models, each selecting a different index melanoma lesion. 1068 stage I and II melanoma patients were followed up for a median of 24.4 years. MPM was found in 17.8% of the cohort (190 patients), more likely among males and older age groups. Other clinicopathological parameters were similar between the MPM and SPM (878 patients) cohorts. After adjustment for age, sex and Breslow thickness, MPM was a hazard for death from melanoma, across all models, reaching significance when considering the last invasive lesion as the index melanoma (HR = 2.76, P = 0.017). Patients with multiple invasive lesions seem more at risk of death from melanoma, independent of known prognostic factors.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Australia 1 6%
Unknown 16 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 29%
Student > Master 4 24%
Student > Ph. D. Student 2 12%
Student > Bachelor 1 6%
Other 1 6%
Other 2 12%
Unknown 2 12%
Readers by discipline Count As %
Medicine and Dentistry 8 47%
Agricultural and Biological Sciences 3 18%
Biochemistry, Genetics and Molecular Biology 2 12%
Nursing and Health Professions 1 6%
Unknown 3 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 April 2015.
All research outputs
#20,656,820
of 25,374,647 outputs
Outputs from Journal of the European Academy of Dermatology & Venereology
#3,864
of 5,367 outputs
Outputs of similar age
#207,162
of 278,951 outputs
Outputs of similar age from Journal of the European Academy of Dermatology & Venereology
#41
of 62 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,367 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.8. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,951 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.