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Chronic thalamic stimulation improves tremor and levodopa induced dyskinesias in Parkinson's disease.

Overview of attention for article published in Journal of neurology, neurosurgery and psychiatry, March 1993
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Title
Chronic thalamic stimulation improves tremor and levodopa induced dyskinesias in Parkinson's disease.
Published in
Journal of neurology, neurosurgery and psychiatry, March 1993
DOI 10.1136/jnnp.56.3.268
Pubmed ID
Authors

D Caparros-Lefebvre, S Blond, P Vermersch, N Pécheux, J D Guieu, H Petit

Abstract

Chronic thalamic stimulation was performed in 10 Parkinsonian patients with disabling tremor and poor response to drug therapy. During the stereotactic procedure, an electrode was introduced in the ventralis intermediate nucleus of the thalamus. Test stimulation was performed during the intra-operative procedure and a few days after surgery using an external stimulator. When tremor was obviously reduced by thalamic stimulation, an internal stimulator was implanted under the clavicle. Tremor was initially suppressed in all cases and reappeared whenever stimulation was stopped. Patients were followed for 22 to 34 months. Tremor was controlled in eight cases but reappeared after three months in two cases. Levodopa induced dyskinesias were observed before electrode implantation in 5 cases. They consisted of peak-dose choreic or ballistic dyskinesias in 4 cases and biphasic dystonic dyskinesias in 3 cases. Peak-dose dyskinesias were greatly improved or suppressed in all cases. Biphasic dyskinesias were improved in 2 cases. Thalamic stimulation was well tolerated. Mild dystonic hand posture related to the deep brain stimulation was observed in one case. No neuropsychological side-effects were noted. Thalamic stimulation could prove to be an adequate treatment for resistant tremor and levodopa induced dyskinesias.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 4%
United States 1 2%
Canada 1 2%
Brazil 1 2%
Unknown 50 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 15%
Researcher 7 13%
Student > Bachelor 5 9%
Other 4 7%
Professor 4 7%
Other 9 16%
Unknown 18 33%
Readers by discipline Count As %
Medicine and Dentistry 13 24%
Neuroscience 9 16%
Agricultural and Biological Sciences 8 15%
Engineering 4 7%
Psychology 2 4%
Other 5 9%
Unknown 14 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 February 1998.
All research outputs
#8,572,103
of 25,460,914 outputs
Outputs from Journal of neurology, neurosurgery and psychiatry
#3,655
of 7,419 outputs
Outputs of similar age
#5,820
of 19,368 outputs
Outputs of similar age from Journal of neurology, neurosurgery and psychiatry
#10
of 15 outputs
Altmetric has tracked 25,460,914 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,419 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.1. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 19,368 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.