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Mendeley readers
Attention Score in Context
| Title |
IL-10-independent regulatory B-cell subsets and mechanisms of action
|
|---|---|
| Published in |
International Immunology, May 2015
|
| DOI | 10.1093/intimm/dxv033 |
| Pubmed ID | |
| Authors |
Avijit Ray, Luman Wang, Bonnie N Dittel |
| Abstract |
Although classically B cells are known to play important roles in immune protection via humoral immunity, recently their regulatory mechanisms have been best appreciated in the context of autoimmunity. Several studies have identified different subsets of regulatory B cells that vary not only in their phenotype, but also in their mechanism of action. Although the best-studied mechanism of B cell immune regulation is IL-10 production, other IL-10-independent mechanisms have been proposed. These include maintenance of CD4(+)Foxp3(+) T regulatory cells (Treg); production of TGF-β, IL-35, IgM or adenosine; or expression of PD-L1 (programmed death 1) or FasL (Fas ligand). Given that B cell-targeted therapy is being increasingly used in the clinic, a complete understanding of the mechanisms whereby B cells regulate inflammation associated with specific diseases is required for designing safe and effective immunotherapies targeting B cells. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 128 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Netherlands | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 125 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 23 | 18% |
| Student > Master | 22 | 17% |
| Student > Ph. D. Student | 19 | 15% |
| Student > Bachelor | 16 | 13% |
| Other | 7 | 5% |
| Other | 22 | 17% |
| Unknown | 19 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 29 | 23% |
| Medicine and Dentistry | 26 | 20% |
| Agricultural and Biological Sciences | 20 | 16% |
| Biochemistry, Genetics and Molecular Biology | 19 | 15% |
| Unspecified | 4 | 3% |
| Other | 8 | 6% |
| Unknown | 22 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 October 2015.
All research outputs
#20,657,128
of 25,374,917 outputs
Outputs from International Immunology
#1,704
of 1,944 outputs
Outputs of similar age
#206,123
of 280,290 outputs
Outputs of similar age from International Immunology
#19
of 21 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,944 research outputs from this source. They receive a mean Attention Score of 5.0. This one is in the 3rd percentile – i.e., 3% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,290 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.