| Title |
Vitamin D levels and parathyroid hormone variations of children living in a subtropical climate: a data mining study
|
|---|---|
| Published in |
Italian Journal of Pediatrics, March 2018
|
| DOI | 10.1186/s13052-018-0479-8 |
| Pubmed ID | |
| Authors |
Ozlem Naciye Sahin, Muhittin Serdar, Mustafa Serteser, Ibrahim Unsal, Aysel Ozpinar |
| Abstract |
Vitamin D and intact parathyroid hormone (iPTH) play a crucial role in calcium homeostasis and bone health of children. Serum level of 25-hydroxyvitamin D (25-OHD) is considered to be the most accurate marker for vitamin D status. However, there have only been a few studies, with limited number of subjects, investigating the relationship between 25-OHD and parathyroid hormone (PTH) in children. The aim of this study was to evaluate the seasonal 25-OHD levels and its associations with intact parathyroid hormone (iPTH) in Turkish children at all pediatric ages; and then to define a critical decision threshold level for 25-OHD deficiency in Turkish children. A retrospective record review of 90,042 children, was performed on serum 25-OHD and for 3525 iPTH levels. They were measured by mass spectrometry method and by electrochemiluminescence immunoassay simultaneously. 25-OHD levels showed a sinusoidal fluctuation througout the year; being significantly higher in summer and autumn (p < 0,01). 25-OHD levels decreased with respect to age. The significant inverse relationship that was found between iPTH and 25-OHD suggests that the inflection point of serum 25-OHD level for maximal suppression of PTH is at 30 ng/ml. As the rate of vitamin D deficiency decreases in the early years due to vitamin D supplementation, the recommendation should be set due to a clinical threshold level of 30 ng/ml for 25-OHD based on PTH levels in children of our population. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 54 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 17% |
| Other | 5 | 9% |
| Student > Postgraduate | 5 | 9% |
| Professor > Associate Professor | 4 | 7% |
| Professor | 3 | 6% |
| Other | 14 | 26% |
| Unknown | 14 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 31% |
| Biochemistry, Genetics and Molecular Biology | 5 | 9% |
| Computer Science | 2 | 4% |
| Agricultural and Biological Sciences | 2 | 4% |
| Neuroscience | 2 | 4% |
| Other | 6 | 11% |
| Unknown | 20 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2018.
All research outputs
#22,767,715
of 25,382,440 outputs
Outputs from Italian Journal of Pediatrics
#861
of 1,060 outputs
Outputs of similar age
#307,183
of 347,622 outputs
Outputs of similar age from Italian Journal of Pediatrics
#18
of 21 outputs
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