| Title |
Intake of fruits and vegetables and risk of cancer of the upper aero-digestive tract: the prospective EPIC-study
|
|---|---|
| Published in |
Cancer Causes & Control, September 2006
|
| DOI | 10.1007/s10552-006-0036-4 |
| Pubmed ID | |
| Authors |
Heiner Boeing, Thomas Dietrich, Kurt Hoffmann, Tobias Pischon, Pietro Ferrari, Petra H. Lahmann, Marie Christine Boutron-Ruault, Francoise Clavel-Chapelon, Naomi Allen, Tim Key, Guri Skeie, Eiliv Lund, Anja Olsen, Anne Tjonneland, Kim Overvad, Majken K. Jensen, Sabine Rohrmann, Jakob Linseisen, Antonia Trichopoulou, Christina Bamia, Theodora Psaltopoulou, Lars Weinehall, Ingegerd Johansson, Maria-José Sánchez, Paula Jakszyn, Eva Ardanaz, Pilar Amiano, Maria Dolores Chirlaque, J. Ramón Quirós, Elisabet Wirfalt, Göran Berglund, Petra H. Peeters, Carla H. van Gils, H. Bas Bueno-de-Mesquita, Frederike L. Büchner, Franco Berrino, Domenico Palli, Carlotta Sacerdote, Rosario Tumino, Salvatore Panico, Sheila Bingham, Kay-Tee Khaw, Nadia Slimani, Teresa Norat, Mazda Jenab, Elio Riboli |
| Abstract |
Epidemiologic studies suggest that a high intake of fruits and vegetables is associated with decreased risk of cancers of the upper aero-digestive tract. We studied data from 345,904 subjects of the prospective European Investigation into Cancer and Nutrition (EPIC) recruited in seven European countries, who had completed a dietary questionnaire in 1992-1998. During 2,182,560 person years of observation 352 histologically verified incident squamous cell cancer (SCC) cases (255 males; 97 females) of the oral cavity, pharynx, larynx, and esophagus were identified. Linear and restricted cubic spline Cox regressions were fitted on variables of intake of fruits and vegetables and adjusted for potential confounders. We observed a significant inverse association with combined total fruits and vegetables intake (estimated relative risk (RR) = 0.91; 95% confidence interval (95% CI) 0.83-1.00 per 80 g/d of consumption), and nearly significant inverse associations in separate analyses with total fruits and total vegetables intake (RR: 0.97 (95% CI: 0.92-1.02) and RR = 0.89 (95% CI: 0.78-1.02) per 40 g/d of consumption). Overall, vegetable subgroups were not related to risk with the exception of intake of root vegetables in men. Restricted cubic spline regression did not improve the linear model fits except for total fruits and vegetables and total fruits with a significant decrease in risk at low intake levels (<120 g/d) for fruits. Dietary recommendations should consider the potential benefit of increasing fruits and vegetables consumption for reducing the risk of cancers of the upper aero-digestive tract, particularly at low intake. |
Mendeley readers
The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 2% |
| Spain | 1 | <1% |
| Tanzania, United Republic of | 1 | <1% |
| Unknown | 98 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 21 | 21% |
| Student > Ph. D. Student | 16 | 16% |
| Student > Master | 10 | 10% |
| Student > Bachelor | 6 | 6% |
| Other | 6 | 6% |
| Other | 18 | 18% |
| Unknown | 25 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 35 | 34% |
| Agricultural and Biological Sciences | 12 | 12% |
| Biochemistry, Genetics and Molecular Biology | 8 | 8% |
| Nursing and Health Professions | 6 | 6% |
| Social Sciences | 3 | 3% |
| Other | 7 | 7% |
| Unknown | 31 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 June 2019.
All research outputs
#1,656,286
of 23,854,458 outputs
Outputs from Cancer Causes & Control
#172
of 2,187 outputs
Outputs of similar age
#2,872
of 68,436 outputs
Outputs of similar age from Cancer Causes & Control
#3
of 17 outputs
Altmetric has tracked 23,854,458 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,187 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.2. This one has done particularly well, scoring higher than 92% of its peers.
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We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.