| Title |
Technique, safety, and feasibility of EUS-guided radiofrequency ablation in unresectable pancreatic cancer
|
|---|---|
| Published in |
Surgical Endoscopy, May 2018
|
| DOI | 10.1007/s00464-018-6217-x |
| Pubmed ID | |
| Authors |
Filippo Scopelliti, Antonio Pea, Rita Conigliaro, Giovanni Butturini, Isabella Frigerio, Paolo Regi, Alessandro Giardino, Helga Bertani, Marina Paini, Paolo Pederzoli, Roberto Girelli |
| Abstract |
Radiofrequency ablation (RFA) is a well-recognized local ablative technique applied in the treatment of different solid tumors. Intraoperative RFA has been used for non-metastatic unresectable pancreatic ductal adenocarcinoma (PDAC), showing increased overall survival in retrospective studies. A novel RFA probe has recently been developed, allowing RFA under endoscopic ultrasound (EUS) guidance. Aim of the present study was to assess the feasibility and safety of EUS-guided RFA for unresectable PDACs. Patients with unresectable non-metastatic PDAC were included in the study following neoadjuvant chemotherapy. EUS-guided RFA was performed using a novel monopolar 18-gauge electrode with a sharp conical 1 cm tip for energy delivery. Pre- and post-procedural clinical and radiological data were prospectively collected. Ten consecutive patients with unresectable PDAC were enrolled. The procedure was successful in all cases and no major adverse events were observed. A delineated hypodense ablated area within the tumor was observed at the 30-day CT scan in all cases. EUS-guided RFA is a feasible and safe minimally invasive procedure for patients with unresectable PDAC. Further studies are warranted to demonstrate the impact of EUS-guided RFA on disease progression and overall survival. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 41 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 8 | 20% |
| Researcher | 5 | 12% |
| Other | 4 | 10% |
| Professor > Associate Professor | 4 | 10% |
| Student > Postgraduate | 3 | 7% |
| Other | 6 | 15% |
| Unknown | 11 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 20 | 49% |
| Agricultural and Biological Sciences | 2 | 5% |
| Unspecified | 1 | 2% |
| Computer Science | 1 | 2% |
| Psychology | 1 | 2% |
| Other | 5 | 12% |
| Unknown | 11 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 May 2018.
All research outputs
#15,513,418
of 23,055,429 outputs
Outputs from Surgical Endoscopy
#3,833
of 6,116 outputs
Outputs of similar age
#208,142
of 326,939 outputs
Outputs of similar age from Surgical Endoscopy
#61
of 97 outputs
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