Title |
Expression plasticity of Phlebotomus papatasi salivary gland genes in distinct ecotopes through the sand fly season
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Published in |
BMC Ecology and Evolution, October 2011
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DOI | 10.1186/1472-6785-11-24 |
Pubmed ID | |
Authors |
Iliano V Coutinho-Abreu, Rami Mukbel, Hanafi A Hanafi, Emad Y Fawaz, Shabaan S El-Hossary, Mariha Wadsworth, Gwen Stayback, Dilkushi A Pitts, Mahmoud Abo-Shehada, David F Hoel, Shaden Kamhawi, Marcelo Ramalho-Ortigão, Mary Ann McDowell |
Abstract |
Sand fly saliva can drive the outcome of Leishmania infection in animal models, and salivary components have been postulated as vaccine candidates against leishmaniasis. In the sand fly Phlebotomus papatasi, natural sugar-sources modulate the activity of proteins involved in meal digestion, and possibly influence vectorial capacity. However, only a handful of studies have assessed the variability of salivary components in sand flies, focusing on the effects of environmental factors in natural habitats. In order to better understand such interactions, we compared the expression profiles of nine P. papatasi salivary gland genes of specimens inhabiting different ecological habitats in Egypt and Jordan and throughout the sand fly season in each habitat. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 2% |
Argentina | 1 | 2% |
Unknown | 39 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 13 | 32% |
Student > Ph. D. Student | 7 | 17% |
Student > Bachelor | 4 | 10% |
Student > Master | 4 | 10% |
Professor > Associate Professor | 3 | 7% |
Other | 5 | 12% |
Unknown | 5 | 12% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 18 | 44% |
Biochemistry, Genetics and Molecular Biology | 4 | 10% |
Veterinary Science and Veterinary Medicine | 4 | 10% |
Environmental Science | 2 | 5% |
Medicine and Dentistry | 2 | 5% |
Other | 4 | 10% |
Unknown | 7 | 17% |