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Selective enhancement of multipotential hematopoietic progenitors in vitro and in vivo by IL-20

Overview of attention for article published in Blood, July 2003
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

Mentioned by

patent
8 patents

Citations

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46 Dimensions

Readers on

mendeley
8 Mendeley
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Title
Selective enhancement of multipotential hematopoietic progenitors in vitro and in vivo by IL-20
Published in
Blood, July 2003
DOI 10.1182/blood-2003-05-1419
Pubmed ID
Authors

Ling Liu, Chunjin Ding, Wei Zeng, Josef G. Heuer, Jonathan W. Tetreault, Timothy W. Noblitt, Giao Hangoc, Scott Cooper, Kellie A. Brune, Ganesh Sharma, Niles Fox, Scott W. Rowlinson, Danise P. Rogers, Derrick R. Witcher, Peter K. Lambooy, Victor J. Wroblewski, James R. Miller, Hal E. Broxmeyer

Abstract

In a search for novel growth factors, we discovered that human interleukin-20 (IL-20) enhanced colony formation by CD34+ multipotential progenitors. IL-20 had no effect on erythroid, granulocyte-macrophage, or megakaryocyte progenitors. IL-20 transgenic mice increased the numbers and cell cycling of multipotential but not other progenitors. IL-20 administration to normal mice significantly increased only multipotential progenitor cells, demonstrating that IL-20 significantly influences hematopoiesis, with specificity toward multipotential progenitors. This is the first cytokine with such specificity identified.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Czechia 1 13%
Unknown 7 88%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 38%
Researcher 2 25%
Professor 1 13%
Student > Master 1 13%
Professor > Associate Professor 1 13%
Other 0 0%
Readers by discipline Count As %
Medicine and Dentistry 3 38%
Agricultural and Biological Sciences 2 25%
Biochemistry, Genetics and Molecular Biology 1 13%
Social Sciences 1 13%
Immunology and Microbiology 1 13%
Other 0 0%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 September 2013.
All research outputs
#5,446,629
of 25,373,627 outputs
Outputs from Blood
#8,284
of 33,239 outputs
Outputs of similar age
#9,530
of 52,568 outputs
Outputs of similar age from Blood
#37
of 179 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 33,239 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 52,568 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 179 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.