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Mendeley readers
Attention Score in Context
| Title |
New PKS-NRPS tetramic acids and pyridinone from an Australian marine-derived fungus, Chaunopycnis sp.
|
|---|---|
| Published in |
Organic and Biomolecular Chemistry, January 2015
|
| DOI | 10.1039/c5ob01058f |
| Pubmed ID | |
| Authors |
Zhuo Shang, Li Li, Breno P. Espósito, Angela A. Salim, Zeinab G. Khalil, Michelle Quezada, Paul V. Bernhardt, Robert J. Capon |
| Abstract |
Chemical analysis of a marine-derived fungus, Chaunopycnis sp. (CMB-MF028), isolated from the inner tissue of a pulmonate false limpet Siphonaria sp., collected from rock surfaces in the intertidal zone of Moora Park, Shorncliffe, Queensland, yielded the tetramic acid F-14329 () and new analogues, chaunolidines A-C (), together with the new pyridinone chaunolidone A (), and pyridoxatin (). Structures inclusive of absolute configurations were assigned to on the basis of detailed spectroscopic analysis, X-ray crystallography, electronic circular dichroism (ECD), biosynthetic considerations and chemical interconversion. Chaunolidine C () exhibits modest Gram-positive antibacterial activity (IC50 5-10 μM), while chaunolidone A () is a selective and potent inhibitor (IC50 0.09 μM) of human non-small cell lung carcinoma cells (NCI-H460). Tetramic acids form metal chelates with Fe(iii), Al(iii), Cu(ii), Mg(ii) and Zn(ii). |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Unknown | 41 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 24% |
| Student > Master | 10 | 24% |
| Researcher | 5 | 12% |
| Student > Bachelor | 2 | 5% |
| Student > Doctoral Student | 2 | 5% |
| Other | 1 | 2% |
| Unknown | 12 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 12 | 29% |
| Agricultural and Biological Sciences | 6 | 14% |
| Biochemistry, Genetics and Molecular Biology | 5 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
| Immunology and Microbiology | 2 | 5% |
| Other | 1 | 2% |
| Unknown | 14 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 January 2016.
All research outputs
#17,568,405
of 25,756,911 outputs
Outputs from Organic and Biomolecular Chemistry
#4,888
of 6,872 outputs
Outputs of similar age
#222,672
of 361,654 outputs
Outputs of similar age from Organic and Biomolecular Chemistry
#291
of 431 outputs
Altmetric has tracked 25,756,911 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,872 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 361,654 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 431 others from the same source and published within six weeks on either side of this one. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.