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Onabotulinum toxin A (Botox) for chronic migraine treatment: an Italian experience

Overview of attention for article published in Neurological Sciences, May 2015
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Title
Onabotulinum toxin A (Botox) for chronic migraine treatment: an Italian experience
Published in
Neurological Sciences, May 2015
DOI 10.1007/s10072-015-2140-2
Pubmed ID
Authors

L. Grazzi, S. Usai

Abstract

Chronic migraine is a common and debilitating headache syndrome. Botulinum neurotoxin, a potent toxin produced by the anaerobic bacterium clostridium botulinum, used largely for treatment of disorders associated with increased muscle tone and hyperhidrosis, is used for patients suffering from chronic migraine. In this study, a group of patients suffering from chronic migraine with medication overuse was treated with onabotulinum toxin A (Botox) to verify its efficacy for chronic migraine. The results confirmed the efficacy of onabotulinum toxin A (Botox) when used at the dosage of 155 UI according to the PREEMPT protocol. Although these results are preliminary, they led to intense efforts to evaluate the analgesic properties of onabotulinum toxin A (Botox) and to assess its use in clinical practice, in particular in migraine field.

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Geographical breakdown

Country Count As %
Brazil 1 3%
Unknown 38 97%

Demographic breakdown

Readers by professional status Count As %
Other 5 13%
Student > Bachelor 5 13%
Researcher 4 10%
Student > Master 4 10%
Student > Ph. D. Student 3 8%
Other 10 26%
Unknown 8 21%
Readers by discipline Count As %
Medicine and Dentistry 17 44%
Neuroscience 3 8%
Business, Management and Accounting 1 3%
Nursing and Health Professions 1 3%
Agricultural and Biological Sciences 1 3%
Other 5 13%
Unknown 11 28%