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X Demographics
Mendeley readers
Attention Score in Context
| Title |
RNAi therapeutics for brain cancer: current advancements in RNAi delivery strategies
|
|---|---|
| Published in |
Molecular BioSystems, January 2015
|
| DOI | 10.1039/c5mb00278h |
| Pubmed ID | |
| Authors |
Meenakshi Malhotra, André Toulouse, Bruno M. D. C. Godinho, David John Mc Carthy, John F. Cryan, Caitriona M. O'Driscoll |
| Abstract |
Malignant primary brain tumors are aggressive cancerous cells that invade the surrounding tissues of the central nervous system. The current treatment options for malignant brain tumors are limited due to the inability to cross the blood-brain barrier. The advancements in current research has identified and characterized certain molecular markers that are essential for tumor survival, progression, metastasis and angiogenesis. These molecular markers have served as therapeutic targets for the RNAi based therapies, which enable site-specific silencing of the gene responsible for tumor proliferation. However, to bring about therapeutic success, an efficient delivery carrier that can cross the blood-brain barrier and reach the targeted site is essential. The current review focuses on the potential of targeted, non-viral and viral particles containing RNAi therapeutic molecules as delivery strategies specifically for brain tumors. |
X Demographics
The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Ireland | 4 | 31% |
| United Kingdom | 2 | 15% |
| Australia | 1 | 8% |
| Thailand | 1 | 8% |
| United States | 1 | 8% |
| France | 1 | 8% |
| Unknown | 3 | 23% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 62% |
| Scientists | 3 | 23% |
| Science communicators (journalists, bloggers, editors) | 1 | 8% |
| Practitioners (doctors, other healthcare professionals) | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Unknown | 53 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 22% |
| Student > Master | 12 | 22% |
| Student > Bachelor | 7 | 13% |
| Researcher | 7 | 13% |
| Student > Doctoral Student | 3 | 6% |
| Other | 6 | 11% |
| Unknown | 7 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 8 | 15% |
| Agricultural and Biological Sciences | 8 | 15% |
| Engineering | 6 | 11% |
| Chemistry | 5 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 7% |
| Other | 12 | 22% |
| Unknown | 11 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 September 2015.
All research outputs
#5,417,482
of 25,756,911 outputs
Outputs from Molecular BioSystems
#271
of 1,773 outputs
Outputs of similar age
#69,762
of 361,654 outputs
Outputs of similar age from Molecular BioSystems
#27
of 234 outputs
Altmetric has tracked 25,756,911 research outputs across all sources so far. Compared to these this one has done well and is in the 78th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,773 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 361,654 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 234 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.