Title |
Synergizing metabolic flux analysis and nucleotide sugar metabolism to understand the control of glycosylation of recombinant protein in CHO cells
|
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Published in |
BMC Biotechnology, October 2011
|
DOI | 10.1186/1472-6750-11-95 |
Pubmed ID | |
Authors |
Susan C Burleigh, Teun van de Laar, Corné JM Stroop, Wout MJ van Grunsven, Niaobh O'Donoghue, Pauline M Rudd, Gavin P Davey |
Abstract |
The glycosylation of recombinant proteins can be altered by a range of parameters including cellular metabolism, metabolic flux and the efficiency of the glycosylation process. We present an experimental set-up that allows determination of these key processes associated with the control of N-linked glycosylation of recombinant proteins. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 166 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 2% |
India | 1 | <1% |
China | 1 | <1% |
Unknown | 160 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 41 | 25% |
Student > Master | 23 | 14% |
Student > Ph. D. Student | 22 | 13% |
Student > Bachelor | 11 | 7% |
Other | 8 | 5% |
Other | 22 | 13% |
Unknown | 39 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 47 | 28% |
Biochemistry, Genetics and Molecular Biology | 26 | 16% |
Chemical Engineering | 14 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 13 | 8% |
Engineering | 11 | 7% |
Other | 14 | 8% |
Unknown | 41 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 September 2021.
All research outputs
#6,375,523
of 22,655,397 outputs
Outputs from BMC Biotechnology
#360
of 935 outputs
Outputs of similar age
#38,581
of 139,128 outputs
Outputs of similar age from BMC Biotechnology
#7
of 16 outputs
Altmetric has tracked 22,655,397 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 935 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 139,128 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.