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Dissemination of clonally related multidrug-resistant Klebsiella pneumoniae in Ireland

Overview of attention for article published in Epidemiology & Infection, June 2015
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Title
Dissemination of clonally related multidrug-resistant Klebsiella pneumoniae in Ireland
Published in
Epidemiology & Infection, June 2015
DOI 10.1017/s0950268815001041
Pubmed ID
Authors

D. MORRIS, M. O'CONNOR, R. IZDEBSKI, M. CORCORAN, C. E. LUDDEN, E. McGRATH, V. BUCKLEY, B. CRYAN, M. GNIADKOWSKI, M. CORMICAN

Abstract

In October 2012, an outbreak of gentamicin-resistant, ciprofloxacin non-susceptible extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae occurred in a neonatal intensive care unit in Ireland. In order to determine whether the outbreak strain was more widely dispersed in the country, 137 isolates of K. pneumoniae with this resistance phenotype collected from 17 hospitals throughout Ireland between January 2011 and July 2013 were examined. ESBL production was confirmed phenotypically and all isolates were screened for susceptibility to 19 antimicrobial agents and for the presence of genes encoding bla TEM, bla SHV, bla OXA, and bla CTX-M; 22 isolates were also screened for bla KPC, bla NDM, bla VIM, bla IMP and bla OXA-48 genes. All isolates harboured bla SHV and bla CTX-M and were resistant to ciprofloxacin, gentamicin, nalidixic acid, amoxicillin-clavulanate, and cefpodoxime; 15 were resistant to ertapenem, seven to meropenem and five isolates were confirmed as carbapenemase producers. Pulsed-field gel electrophoresis of all isolates identified 16 major clusters, with two clusters comprising 61% of the entire collection. Multilocus sequence typing of a subset of these isolates identified a novel type, ST1236, a single locus variant of ST48. Data suggest that two major clonal groups, ST1236/ST48 (CG43) and ST15/ST14 (CG15) have been circulating in Ireland since at least January 2011.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 42 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 31%
Student > Bachelor 5 12%
Student > Ph. D. Student 4 10%
Professor > Associate Professor 3 7%
Student > Master 3 7%
Other 5 12%
Unknown 9 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 24%
Medicine and Dentistry 10 24%
Immunology and Microbiology 6 14%
Biochemistry, Genetics and Molecular Biology 3 7%
Business, Management and Accounting 1 2%
Other 0 0%
Unknown 12 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 June 2015.
All research outputs
#19,945,185
of 25,377,790 outputs
Outputs from Epidemiology & Infection
#3,780
of 4,680 outputs
Outputs of similar age
#189,704
of 278,181 outputs
Outputs of similar age from Epidemiology & Infection
#30
of 52 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,680 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,181 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 52 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.