Title |
CRISPR/Cas13a targeting of RNA virus in plants
|
---|---|
Published in |
Plant Cell Reports, May 2018
|
DOI | 10.1007/s00299-018-2297-2 |
Pubmed ID | |
Authors |
Kul Bhushan |
Abstract |
This approach is quite promising to control plant viral diseases and create synthetic networks to better understand the structure/function relationship in RNA and proteins. Plant viruses are obligate intracellular parasites which causes enormous losses in crop yield worldwide. These viruses replicate into infected cells by highjacking host cellular machinery. Over the last two decades, diverse approaches such as conventional breeding, transgenic approach and gene silencing strategies have been used to control RNA viruses, but escaped due to high rate of mutation. Recently, a novel CRISPR enzyme, called Cas13a, has been used engineered to confer RNA viruses resistance in plants. Here, we summarize the recent breakthrough of CRISPR/Cas13a and its applications in RNA biology. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 2 | 13% |
United States | 1 | 7% |
Brazil | 1 | 7% |
United Kingdom | 1 | 7% |
Netherlands | 1 | 7% |
Japan | 1 | 7% |
Canada | 1 | 7% |
Unknown | 7 | 47% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 11 | 73% |
Scientists | 3 | 20% |
Science communicators (journalists, bloggers, editors) | 1 | 7% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 41 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 8 | 20% |
Researcher | 7 | 17% |
Student > Bachelor | 4 | 10% |
Student > Postgraduate | 4 | 10% |
Student > Master | 3 | 7% |
Other | 6 | 15% |
Unknown | 9 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 14 | 34% |
Agricultural and Biological Sciences | 13 | 32% |
Arts and Humanities | 1 | 2% |
Computer Science | 1 | 2% |
Immunology and Microbiology | 1 | 2% |
Other | 1 | 2% |
Unknown | 10 | 24% |